Aalto University, P.O. Box 11000, FI-00076 Aalto www.aalto.fi Author Tiina Nypelö Name of the doctoral dissertation Surface-modified nanoparticles for ultrathin coatings Publisher Aalto University School of Chemical Technology Unit Department of Forest Products Technology Series Aalto University publication series DOCTORAL DISSERTATIONS 12/2012 Field of research Forest Products Chemistry Manusc...

The environmental effects of nanoplastics-NPLs have been addressed mainly through short-term exposures to a few types polymers, neglecting other NPLs that are economically relevant like polymethylmethacrylate - PMMA. This work aimed assess long-term PMMA-NPLs on the marine primary consumer Brachionus plicatilis, evaluating influence different exposure routes (waterborne, foodborne and both) foo...

Exposure to nanosized particles may increase the risk of cardiovascular diseases by endothelial dysfunction, particularly in susceptible subjects with metabolic syndrome. We investigated vasomotor dysfunction in aorta from obese and lean Zucker rats after oral exposure to nanosized carbon black (CB). Rats were exposed to 1 or 10 weekly doses of 0, 0.064, 0.64 or 6.4 mg/kg bodyweight and sacrifi...

BACKGROUND Enhancing drug delivery is an ongoing endeavor in pharmaceutics, especially when the efficacy of chemotherapy for cancer is concerned. In this study, we prepared and evaluated nanosized HKUST-1 (nanoHKUST-1), nanosized metal-organic drug delivery framework, loaded with 5-fluorouracil (5-FU) for potential use in cancer treatment. MATERIALS AND METHODS NanoHKUST-1 was prepared by rea...

In this paper the humidity sensing properties of layers prepared by a new method for obtaining doped tin oxide are studied. Different techniques-SEM, EDS in SEM, TEM, SAED, AES and electrical measurements-are used for detailed characterization of the thin layers. The as-deposited layers are amorphous with great specific area and low density. They are built up of a fine grained matrix, consistin...

Medically, the oil-in-water nanosized emulsions are used mainly as delivery carriers for lipophilic drug molecules which show therapeutic activity when administered via parenteral, ocular and transdermal routes. To extract multifunctional activities, the nanosized emulsions containing neutral, anionic and cationic charges over dispersed oil droplets are designed with the help of variety of exci...