abstract background: in developing countries, hemorrhage accounts for 30% of the maternal deaths. postpartum hemorrhage has been defined as blood loss of around 500 ml or more, after completing the third phase of labor. most cases of postpartum hemorrhage occur during the first hour after birth. the most common reason for bleeding in the early hours after childbirth is uterine atony bleeding du...

background: nasal inflammatory disorders such as chronic rhinosinusitis and nasal polyp are among the most prevalent complications with high socioeconomic costs. vascular endothelial growth factor (vegf) plays a key role in angiogenesis and cell proliferation. in the present study the effect of vegf on the development and prognosis of chronic rhinosinusitis and nasal polyp was investigated. met...

introduction: the objective of this retrospective cross-sectional study was to obtain epidemiological data from the charts of 297 patients with nasal polyposis who were operated on in a referral hospital in mashhad and to determine the frequency of the presenting symptoms of nasal polyps.  materials and methods: the variables recorded included age, gender, the presence of asthma or allergic rhi...

Because of the location, skull-base chordomas often present with headaches and diplopia and sixth and fifth nerve palsies are the most common neurological signs.[1,2] The interval between onset of symptoms and diagnosis of clival chordoma is quite variable, 2.5-4.4 years.[4] The uncommon clinical presentations include: Nasal obstruction, nasal bleeding, and subarachnoid hemorrhage.[3,5] Spontan...

A 36-year-old right-handed male construction worker presented 2 days after feeling a sudden pain in his right maxillary area while using a nail gun. At that time, he thought that the nail gun flew up and hit him in the face without discharging a nail. He noted only mild pain and a small abrasion on his right cheek. Over the subsequent days he developed progressively worse pain and swelling of h...

OBJECTIVE To compare the efficacy of prophylactic vs postoperative antibiotic use in complex septorhinoplasty and strengthen the evidence base for antibiotic use in nasal surgery. DESIGN A randomized, prospective, single-blinded trial. One hundred sixty-four patients requiring complex septorhinoplasty surgery were recruited sequentially from the waiting lists of the 2 senior authors. Power wa...

In this study, we evaluated the inhalation toxicity of acetaldehyde in Aldh2 KO (Aldh -/-) mice, using pathological method. Male C57BL/6 (Aldh2 +/+) mice and Aldh -/- mice were exposed to atmospheres containing acetaldehyde at levels of 0, 125, and 500 ppm for 24 h/day during 14 days. Although the average blood acetaldehyde concentration of Aldh -/- mice was higher than that of Aldh2 +/+ mice i...

Hereditary hemorrhagic telangiectasia (HHT) is mechanistically and therapeutically challenging, not only because of the molecular and cellular perturbations that generate vascular abnormalities, but also the modifications to circulatory physiology that result, and are likely to exacerbate vascular injury. First, most HHT patients have visceral arteriovenous malformations (AVMs). Significant vis...