Nasopharyngeal cancer patients with stage I – IV will cause painful symptoms such as signs of swelling due to the growth abnormal tissue in nasopharynx. Symptoms nasopharyngeal can interfere daily activities, fulfillment needs, and need for rest. The dependence is very minimal carry out activities both physically, psychologically, socially, control disease or related treatment care. This study ...

BACKGROUND Cyclin D1 and p16 are involved in the regulation of G1 checkpoint and may play an important role in the tumorigenesis of nasopharyngeal carcinoma (NPC). Previous studies have examined the level of expression of cyclin D1 and p16 in primary untreated NPC but no such information is available for recurrent NPC. We set out in this study to examine the expression level of cyclin D1 and p1...

We report a patient with nasopharyngeal cancer with long-term follow-up of more than 16 years after the first course of radiotherapy in 1981. He developed a lung metastasis in 1996 after having a second course of radiotherapy for neck recurrence in 1989. The patient was a 42-year-old man with a nasopharyngeal tumor and a fixed upper neck metastasis (T1N1M0), which was treated with definitive ra...

It is widely accepted that a mucosal ulcer induced by radiation (RIMU) is the predominant type of post-radiation nasopharyngeal ulcer in patients with nasopharyngeal carcinoma (NPC) who underwent radiotherapy (RT); however, another type of ulcer, an ulcer of post-radiation nasopharyngeal necrosis (UPRNN), has rarely been reported for patients with NPC. In the present study, the clinical and ima...

Probe-based confocal laser endomicroscopy (pCLE) is a method that produces microscopic imaging of lung tissue during bronchoscopy. We report case ot patient with negative nasopharyngeal swabs and suspected cancer who underwent pCLE. The diagnosis COVID-19 was confirmed by PCR analyses lavage fluid transbrohial biopsy. pCLE image shows density alveolar thickened fibres, disorganization elastin n...

Nasopharyngeal carcinoma (NPC) is a common cancer in Southeast Asia, for which radiotherapy and/or chemotherapy are the primary treatment methods. Many herbs are known to have potential uses in chemotherapy; however, the mechanisms underlying the observed antitumor activity of Ajuga bracteosa (AB) against NPC remain unclear. We explored the antitumor effects of AB, which was shown specifically ...

In industrial workers, formaldehyde exposure has been associated with cancer of the nasal cavities, nasopharynx, prostate, lung, and pancreas; however, these associations are inconsistent and remain controversial. Animals exposed to formaldehyde show excesses of nasal cancer. In an extended follow-up of a large cohort of formaldehyde-exposed workers, the authors evaluated mortality from solid c...

Interleukin-10 (IL10) is an immunosuppressive cytokine which may facilitate carcinogenesis by down-regulating interferon-gamma production and supporting tumor escape from the immune response. Polymorphisms within the promoter of IL10 gene may not only contribute to differential IL10 expression levels among individuals but also to oral cancer susceptibility. In this hospital-based study, the ass...

Radiotherapy is one of the main treatments for head and neck cancers, especially nasopharyngeal cancer. During radiotherapy, the salivary glands, parts of which are commonly included in or very close to the target volume, receive a high radiation dose on both sides, which can lead to xerostomia (dry mouth). Xerostomia can produce a number of negative effects on the patient’s quality of life, af...

Epstein-Barr virus (EBV) is associated with multiple types of human cancer, including lymphoid and epithelial cancers. The closest association with EBV infection is seen in undifferentiated nasopharyngeal carcinoma (NPC), which is endemic in the southern Chinese population. A strong association between NPC risk and the HLA locus at chromosome 6p has been identified, indicating a link between th...