Oxidative stress is considered to be a mechanism of major depression. Pycnogenol (PYC) is a natural plant extract from the bark of Pinus pinaster Aiton and has potent antioxidant activities. We studied the ameliorative effect of PYC on depression-like behavior in chronic corticosterone- (CORT-) treated mice for 20 days. After the end of the CORT treatment period, PYC (0.2 mg/mL) was orally admi...

How natural disasters affect the psychological state of adolescents has not been well studied. Thus, we examined the effect of a natural disaster on high-school-aged youth and considered the most effective forms of support following such a disaster. We examined students from two high schools that were near the epicenter of the 9.0-magnitude Great East Japan Earthquake, which struck the Tohoku c...

One symptom of depression is loss of motivation, which can be defined as responsiveness to response-eliciting stimuli and quantified as reward-related behavioral output. Long-term changes in reward-related behavior have been shown to follow early life stress. Most rodent studies investigating the effects of postnatal separation, an early stress, on reward-related behavior have used drug rewards...

BACKGROUND Earthquakes can result in a range of psychopathology and in negative and positive consequences for survivors. OBJECTIVE To examine the association between clinical aftereffects (anxiety and depressive symptoms) and post-traumatic growth (PTG) among young survivors of the 2009 L'Aquila earthquake, Italy. METHOD 316 young earthquake survivors enrolled in the University of L'Aquila ...

OBJECTIVE To determine the rates of psychiatric disorder and personality variables in a sample of older people who had committed suicide and to compare the rates in a subgroup of this sample with those in a control group of people who died from natural causes. DESIGN Descriptive psychological autopsy study, including interviews with informants, of psychiatric and personality factors in 100 su...

Purpose: Depression is a sickening psychiatric condition that is prevalent worldwide. To manage depression, the underlying modes of antidepressant effect of herbals are important to be explored for the development of natural drugs. Tiansi Liquid is a traditional Chinese medicine (TCM) that is prescribed for the management of depression, however its underlying mechanism of action is still uncert...

background: after each natural disaster a comprehensive treatment protocol is needed for volunteers of healthcare personnel of the disaster zone. the aim of this study was to emphasize the psychological aspects of coping strategies, personality, psychological distress and pain of patients survived the bam earthquake.   methods: eighty-six patients who had suffered several kinds of psycho-cognit...

OBJECTIVE This study evaluates the capacity of the Edinburgh Postnatal Depression Scale (EPDS) implemented in the first days postpartum to detect women who will suffer from postnatal depression. METHOD A sample of 1154 women completed the EPDS at 2 to 3 days postpartum and again at 4 to 6 weeks postpartum. RESULTS There was a highly significant positive correlation between EPDS scores on bo...

OBJECTIVE The aim of this study is to estimate the prevalence of postnatal depression in Nuuk, Greenland. STUDY DESIGN Cross-sectional study. METHODS The primary health care system in Nuuk initiated a project aiming to screen new mothers for depression using the Edinburgh Postnatal Depression Scale (EPDS). EPDS has a range on a scale from 0 to 30. All mothers residing in Nuuk who had given ...