nec is inflammatory necrosis of intestine with most common site being terminal ileum and ascending colon in preterm babies (1). the condition is typically seen in premature infants, and the timing of its onset is generally inversely proportional to the gestational age of the baby at birth, i.e. the earlier a baby is born, longer is the time of risk for nec in premature babies. the incidence of ...

The granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN). The antinuclear (ANA) and...

how to cite this article: salehi omran mr, nooreddini h, baghdadi f. acute necrotizing encephalopathy of childhood; a case report. iran j child neurol. 2013 spring;7(2):51-54.   abstract acute necrotizing encephalopathy of childhood (anec) is an atypical disease followed by respiratory or gastrointestinal infection, high fever, which is accompanied with rapid alteration of consciousness and sei...

Arterial thrombosis associated with ulcerative colitis usually occurs in the postoperative period with a good response to anticoagulant therapy and embolectomy. Our patient was a 14-year-old girl with ulcerative colitis who presented with bilateral pulsless extremities, which did not respond to medical treatment and embolectomy. Subsequent colectomy did not save her limbs. The repeated thrombos...

Skin is a frequently involved and damaged organ in cutaneous necrotizing vasculitis (CNV), mainly characterized histologically by segmental angiocentric inflammatory condition with fibrinoid necrosis of the vessel wall. Various etiological factors have been described as probable causes that trigger CNV, ranging from infectious to autoimmune conditions. We case middle-aged man chronic kidney dis...