Within a cohort of 1,915 consecutive patients with myeloproliferative neoplasm followed for a median time of 5.2 years (range 0-33.3), we investigated the occurrence of lymphoid neoplasm with the aim of defining this risk and to investigate the role of genetic predisposing factors. We identified 22 patients with myeloproliferative neoplasm who developed lymphoid neoplasm over their lifetime. We...

In traditional Genetic Algorithm, random population seeding technique is simple and efficient however the population may contain poor quality individuals which take long time to converge optimal solution. This motivates to design a population initialization technique with the features of randomness, individual diversity and good quality. In this paper, an initial work has been carried out to de...

This dissertation presents a study of injection seeding in Nd:YLF Q-switched oscillators for the purposes of producing single axial mode output. The objective was to develop a prototype system and determine the limiting factors which dictate successful injection seeding. The laser system consisted of a laser diode pumped monolithic miniature Nd:YLF master oscillator which seeded a conventional ...

Cloned human telomeric DNA can integrate into mammalian chromosomes and seed the formation of new telomeres. This process occurs efficiently in three established human cell lines and in a mouse embryonic stem cell line. The newly seeded telomeres appear to be healed by telomerase. The seeding of new telomeres by cloned telomeric DNA is either undetectable or very inefficient in non-tumourigenic...

Subcutaneous tumor seeding after fine-needle percutaneous biopsy for hepatocellular carcinoma is a rarely seen complication. The authors describe a case of subcutaneous neoplastic seeding in a 70-year-old woman with chronic hepatitis C virus complicated by hepatocellular carcinoma. Ultrasonically guided fine-needle aspiration biopsy was performed in segment II of the liver. The neoplastic seedi...

Increased soybean seed cost in recent years has generated interest in reducing seeding rates to maintain consistent economic returns. However, low seeding rates result in reduced established plant stands with slower canopy development, and canopy development is touted as an important element of integrated weed management (IWM). IWM practices have become even more important to slow the developme...

In this paper, we present experimental results supporting early work on the Seeding Genetic Algorithm. We evaluate the algorithm’s performance with various parameterisations, making comparisons to the Canonical Genetic Algorithm, and use these as guidelines as we establish reasonable parameters for the seeding algorithm. We discuss how experimental results complement and confirm aspects of the ...

Ovarian sex cord-stromal tumors are relatively infrequent neoplasms that account for approximately 8% of all primary ovarian neoplasm. Sex cord-stromal tumors of the ovary include granulosa cell tumors, fibrothecomas, Sertoli-Leydigcell tumors, steroid cell tumors, and sclerosing stromal tumors (SST). Sclerosing stromal tumors account for 2% to 6% of ovarian stromal tumors. Despite the rarity o...

The number of new gastric cancer (GC) cases is decreasing, and these patients have longer survival thanks to new oncological treatments. In advanced GC a common evolution of this neoplasm is peritoneal metastases (PM). In the past this finding meant no chance for cure. However, today, using high quality operations and HIPEC, we are able to increase the number of patients treated with curative i...

BACKGROUND Plaque radiotherapy is the most common method of managing posterior uveal melanoma but its use for iris melanoma and iris metastases has not yet been evaluated. METHODS Fourteen patients with non-resectable iris melanoma and four with iris metastasis were treated with plaque radiotherapy. The tumour response to treatment and the local side effects of the radioactive plaque were eva...