It has been shown by Hodgkin (1939) that a change of resistance on the outside of a nerve fibre is followed by a change in conduction velocity. This effect was obtained (i) by altering the volume of saline surrounding the fibre, (ii) by placing a metal shunt in parallel with it. In the present paper, similar changes of conduction velocity are described following the replacement of electrolytes ...

Twenty-two patients with ulnar nerve palsy at the elbow, confirmed by electromyography, were treated by a night splint which prevented flexion of the elbow beyond 60 degrees. The splint was worn all night regularly for at least six months. At a mean follow-up of 11.3 months, 17 patients had clinical and electromyographic assessment and five were contacted by telephone. There was improvement in ...

E ntrapment neuropathy of the common peroneal nerve is caused mostly by compression at the fibula head region. In cases of severe axon loss, demonstration of conduction block or reduction of conduction velocity would be difficult. Apart from demyelination, mechanical factors and ischemic mechanisms may play a role. Differing degrees of damage to individual nerve fascicles may occur within the c...

By measuring the distribution of conduction velocities (DCV) in sensory fibres of the median nerve, the effects of local vibration on all faster and slower large myelinated nerve fibres were examined in 10 male chain saw operators (three operators had frequent attacks of white finger; the attacks were only occasional in four and negative in three). All parameters of DCV, and conventional sensor...

It was the object of this study to measure the time course of the action potential in individual human sensory nerve fibres in relation to conduction properties of the axons. For this purpose, the technique of percutaneous microneurography was combined with intradermal electrical stimulation of distal portions of the axons. Recordings were made at the wrist level from 57 type-identified mechano...

In the carpal tunnel syndrome median nerve motor conduction may be delayed below the wrist, while the motor nerve fibre conduction velocity above-the wrist may be relatively unaffected (Carpendale, 1956; Simpson, 1956). Median nerve sensory conduction may also be impaired below the wrist in the carpal tunnel syndrome (Gilliatt and Sears, 1958). No detailed study has been made comparing distal s...

Twenty lead-exposed men were selected on the basis of a maximum level of lead in the blood of 70-140 ,tg/l00 ml within the past year. There was no clinical evidence of neuropathy attributable to lead and haemoglobin levels were normal. In individuals, maximum motor and sensory conduction and the amplitude of the evoked potentials were normal or borderline in the median, peroneal and sural nerve...

The abnormalities underlying diabetic neuropathy appear to be multiple and involve metabolic neuronal and vasomediated defects. The accumulation of long-chain fatty acids and impaired b -oxidation due to deficiencies in carnitine and/or its esterified derivatives, such as acetylL -carnitine, may have deleterious effects. In the present study, we examined, in the diabetic bio-breeding Worcester ...