نتایج جستجو برای: net reclassification improvement
تعداد نتایج: 406535 فیلتر نتایج به سال:
BACKGROUND Framingham risk equations are widely used to predict cardiovascular disease based on health information from a single time point. Little is known regarding use of information from repeat risk assessments and temporal change in estimated cardiovascular risk for prediction of future cardiovascular events. This study was aimed to compare the discrimination and risk reclassification of a...
BACKGROUND Weights assigned to comorbidities to predict mortality may vary based on the type of index disease and advances in the management of comorbidities. We aimed to develop a modified Charlson comorbidity index (CCI) in incident hemodialysis patients (mCCI-IHD), thereby improving risk stratification for mortality. METHODS Data on 24,738 Koreans who received their first hemodialysis trea...
OBJECTIVE We investigated the association of ankle-brachial blood pressure index (ABI), interarm blood pressure (BP) difference and interankle BP difference, obtained by simultaneous four-limb BP measurement, with history of stroke in a Chinese adult population. METHODS This cross-sectional study included 1485 participants aged ≥35 years in the framework of the China Hypertension Survey. We p...
IMPORTANCE AND OBJECTIVE Besides their role in diagnosis of acute myocardial infarction (MI), troponins may be powerful biomarkers for risk stratification in the general population. The objective of our study was to compare the performance of three troponin assays in cardiovascular disease (CVD) risk prediction in a population-based cohort without a history of CVD events. DESIGN, SETTING AND ...
INTRODUCTION Prior studies have demonstrated a decline in the predictive ability of conventional risk factors (RF) with advancing age, emphasizing the need for novel tools to improve risk stratification in the elderly. Coronary artery calcification (CAC) is a robust predictor of adverse cardiovascular events, but its long-term prognostic utility beyond RFs in elderly persons is unknown. METHO...
BACKGROUND Risk prediction in elderly patients is increasingly relevant due to longer life expectancy. OBJECTIVES This study sought to examine whether electrocardiographic (ECG) changes provide prognostic information incremental to current risk models and to the conventional risk factors. METHODS In all, 6,991 participants from the Copenhagen Heart Study attending an examination at age ≥65 ...
OBJECTIVE To develop and validate a novel comorbidity score (multisource comorbidity score (MCS)) predictive of mortality, hospital admissions and healthcare costs using multiple source information from the administrative Italian National Health System (NHS) databases. METHODS An index of 34 variables (measured from inpatient diagnoses and outpatient drug prescriptions within 2 years before b...
BACKGROUND Inflammation, coagulation, and cell stress contribute to atherosclerosis and its adverse events. A biomarker risk score (BRS) based on the circulating levels of biomarkers C-reactive protein, fibrin degradation products, and heat shock protein-70 representing these 3 pathways was a strong predictor of future outcomes. We investigated whether soluble urokinase plasminogen activator re...
OBJECTIVES This study examined the performance of percent aggregate plaque volume (%APV), which represents cumulative plaque volume as a function of total vessel volume, by coronary computed tomography angiography (CTA) for identification of ischemic lesions of intermediate stenosis severity. BACKGROUND Coronary lesions of intermediate stenosis demonstrate significant rates of ischemia. Coron...
AIMS We validated and compared transluminal attenuation gradient (TAG) and corrected coronary opacification (CCO) of coronary computed tomography angiography (CCTA) with invasively measured fractional flow reserve (FFR). BACKGROUND One of the major limitations of CCTA is the discrepancy between angiographical stenosis and ischaemia-causing stenosis. Recently two new CCTA analysis methods, TAG...
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