The human roseoloviruses, human herpesviruses 6A (HHV-6A), HHV-6B, and HHV-7, are highly prevalent viruses that typically cause fever/rash illnesses such as roseola during early life primary infections. They also cause significant neurologic disease and complications following stem cell and solid organ transplantation, and have suggestive but less certain etiologic associations with other neuro...

• Neurologic complications can follow primary EBV infection, although these are rare. should be considered as a precipitant of unexplained mononeuritis multiplex. serology requires repeating and careful interpretation to demonstrate evolution antibody responses confirm the diagnosis. A 20 year old lady presented acute medical unit with new neurological deficits. She described gastrointestinal s...

purpose: to evaluate the etiologies of excessive blinking in children and teenagers less than 18 years of age in hamedan, iran. methods: this study was performed during 2009-2010 as a cross-sectional study on 50 children and teenagers less than 18 years old who were referred to sheikh-al-reis and farshchian clinics in hamedan for abnormal and excessive blinking. ophthalmic and neurologic examin...

Abstract Background Treatments are often unavailable for rare disease patients, especially in low-and-middle-income countries. Reasons this include lack of financial support therapies and onerous regulatory requirements approval drugs. Other barriers reimbursement, administrative infrastructure, knowledge about diagnosis drug treatment options. The International Rare Diseases Research Consortiu...

OBJECTIVE Genetic disorders enter the differential diagnosis of common neurologic diseases, but their overall prevalence is not known. We set out to determine their minimum prevalence. METHODS Meta-analysis of epidemiologic data gathered from the same geographic region in the North of England. RESULTS Monogenic neurologic disorders affect at least 90.9/100,000 (95% confidence interval 87.6-...

OBJECTIVE: To report a rare case of a child with essential primary Cutis verticis gyrata. REPORT: Nine-year-old boy with extensive hypertrophy of scalp skin, with a cerebriform appearance. No underlying neurologic and ophthalmologic disorders were found, and no other cases were described in his family. COMMENTS: The diagnosis of primary Cutis verticis gyrata was established by thickening of the...

OBJECTIVE To evaluate electrocardiographic abnormalities in patients with neurologic diseases. METHODS We studied 161 patients with neurologic disorders by analyzing the 12-lead electrocardiogram during the pathological process. An expert who did not know anything about the patients evaluated the traces. RESULTS Neurological process included brain tumor (41%), stroke (27.3%), cerebral aneur...

The vestibular system is responsible for keeping an animal oriented with respect to gravity. It is a sensory system that maintains the position of the eyes, body, and limbs in reference to the position of the head. Proper interpretation of neurologic deficits and precise neuroanatomic localization are essential to diagnose and prognosticate the underlying disorder. Neurologic examination can co...

Introduction Available data concerning various neurologic disease entities occurring in West African are still appalling scanty, such that a vigorous effort seems urgently essential in the next few years to rectify this lag. In various parts of Nigeria, like much elsewhere in Africa, much neurologic problems presently remain inadvertently neglected for the more pressing consideration of the com...

isocitric dehydrogenase (ICD) activity of the cerebrospinal fluid was measured on 88 children with various disorders of the central nervous system and on 19 children with non-neurologic diseases , the latter serving as controls. The cerebrospinal fluid ICD activity ranged from 0.9 to 7 .7 units with a mean of 4.2•}2.1 units in the control series, and was elevated in 7 out of 33 patients with ce...