CLINICAL QUESTION What is the best treatment for artemisinin-resistant malaria? RESULTS There is still no better treatment than the presently used artemisinin-based combination therapies. A new antimalarial drug for this problem needs to be found. IMPLEMENTATION Pitfalls to avoid when treating drug-resistant malaria:

The microbial world is complex, dynamic and constantly evolving. Infectious agents reproduce rapidly, mutate frequently, cross the species barrier between animal hosts and humans, and adapt with relative ease to their new environments. Because of these traits, infectious agents are able to alter their epidemiology, their virulence, and their susceptibility to anti-infective drugs. When disease ...