The past year has witnessed refinements in models of spliceosome assembly pathways and in the understanding of how splicing factors of the serine/arginine-rich (SR) protein family function. The role of splicing in human genetic diseases has also received a lot of attention recently as exonic splicing enhancers become better understood.

Of course, from childhood to forever, we are always thought to love reading. It is not only reading the lesson book but also reading everything good is the choice of getting new inspirations. Religion, sciences, politics, social, literature, and fictions will enrich you for not only one aspect. Having more aspects to know and understand will lead you become someone more precious. Yea, becoming ...

T elusive dream of replacing missing teeth with artificial analogs has been part of dentistry for a thousand years. The coincidental discovery by Dr P-I Brånemark and his coworkers of the tenacious affinity between living bone and titanium oxides, termed osseointegration, propelled dentistry into a new age of reconstructive dentistry. Initially, the essential tenets for obtaining osseointegrati...

In business, as in the government and tertiary sectors, unlocking mechanisms for ‘life-long’ learning is without question one of the major challenges of today. Each of these sectors must recognise the criticality of preparing people for the world as it is and it is likely to be as opposed to that which is rapidly vanishing. Institutions which fail to grasp this reality have what is surely a bri...

Most nuclear physics ranges from insensitive to relatively insensitive to many-nucleon forces. The dominant ingredient in calculations of nuclear properties is the nucleonnucleon potential. Three-nucleon forces nevertheless play an important role in nuclear physics because of the great precision of modern calculational methods for systems of relatively few nucleons. We explore the reasons why m...

1 SDL is the premier language for specification, design and development of real time systems, and in particular for telecommunication applications. SDL-2000 became the international standard in force in November 1999, replacing the previous version. This paper gives an overview of SDL-2000 and fills the gap between previously published tutorials and the current SDL standard.

2 AI in a New Millennium: Obstacles & Opportunities 2 2.1 AI as both Science and Engineering . . . . . . . . . . . . . . . . . . . . 2 2.2 Difficulties and how to address them. . . . . . . . . . . . . . . . . . . . . 4 2.3 Institutional and financial obstacles . . . . . . . . . . . . . . . . . . . . . 4 2.4 Failing to see problems: ontological blindness . . . . . . . . . . . . . . . 5 2.4.1 Wha...

The future of diagnostic imaging will rely, in large part, on the digital revolution that is currently affecting all technologydriven disciplines. Superimposed on the digital substrate, however, are a variety of wide-ranging developments that are modality-specific advancements in image receptor technology and modality-specific image data reduction. Diagnostic imaging is classically divided into...