BACKGROUND AND THE PURPOSE OF THE STUDY It has been shown that Nigella sativa L. and Portulaca oleracea L. have many antioxidant components. In the present study, the cytoprotective effect of ethanolic and aqueous extracts of N.sativa and P.oleracea against hemolytic damages induced by free radical initiator, AAPH [2, 2' azobis (2- amidinopropane) hydrochloride] was evaluated. METHODS Hemolys...

Over many centuries humans have been mining the bounties of nature for discovering substances that have been used for the treatment of all human diseases; many such remedies are useful even today as modern day medicine. Emerging evidence also suggests that the search is still continuing for harnessing active compounds from nature in combating human illnesses although pharmaceutical industries a...

BACKGROUND In previous studies, the bronchodilator and antitussive effects of Nigella sativa have been demonstrated on guinea pigs. OBJECTIVES In the present study, the effect of the hydroethanolic extract of N. sativa on tracheal responsiveness in guinea pigs exposed to cigarette smoke was examined. MATERIALS AND METHODS Three groups of guinea pig models of COPD were given drinking water a...

Nigella sativa (N. sativa) is a spice plant which has been traditionally used for culinary and medicinal purposes. Different therapeutic properties including the beneficial effects on asthma and dyspnea, digestive and gynecology disorders have been described for the seeds of N. sativa. There is evidence of the relaxant effects of this plant and some of its constituents on different types of smo...

Aim: To study the effect of palm oil and Nigella sativa on the aorta and coronary arteries of albino rats. Methods: Sixty albino rats including equal number of males and females were obtained from PCSIR Laboratories, Lahore. After overnight fasting of 12-14 hour all the animals were weighed and zero and 24 weeks. The rats were divided into five groups of twelve animals each. Each group had six ...

BACKGROUND Osteoporosis poses a significant public health issue. It is a skeletal disorder characterized by compromised bone strength that predisposes to increased risk of fracture. There is a direct relationship between the lack of estrogen after menopause and the development of osteoporosis. About 33% of women over 50 will experience bone fractures as a result of osteoporosis. Nigella Sativa ...

Metronidazole (MTZ) was the most widely accepted treatment for Blastocystis hominis (B. hominis) with high treatment failure rate, resistance and potential mutagenic and carcinogenic effects so there is urgent need to find out new, effective and safe treatment against B. hominis. The present research aimed to evaluate the therapeutic effect of the aqueous extract of Nigella sativa (NS) at diffe...

background: in this study, the protective effect of thymoquinone (tq) and nigella sativa seeds oil (nso) was evaluated against oxidative damages induced by ethanol in rats. methods: animals were treated with ethanol 40% daily by gavages once a day for 4 weeks. nso and tq were injected intraperitoneal once a day for 4 weeks. the histopathological examination of liver, kidney, brain and heart was...

objective: neuroimmune factors contribute on the pathogenesis of sickness behaviors. nigella sativa (ns) has anti-inflammatory, anti-anxiety and anti-depressive effects. in the present study, the effect of ns hydro-alcoholic extract on sickness behavior induced by lipopolysaccharide (lps) was investigated. materials and methods: the rats were divided into five groups (n=10 in each): (1) control...