Nonalcoholic fatty liver disease (NAFLD), a form of chronic that occurs in individuals with no significant alcohol abuse, has become an increasing concern for global health. NAFLD is defined as the presence lipid deposits hepatocytes and it ranges from hepatic steatosis (fatty liver) to steatohepatitis. Emerging data both preclinical studies clinical trials suggest peroxisome proliferator-activ...

Nonalcoholic fatty liver disease (NAFLD) is defined as the presence of hepatic fat accumulation after the exclusion of other causes of hepatic steatosis, including other causes of liver disease, excessive alcohol consumption, and other conditions that may lead to hepatic steatosis. NAFLD encompasses a broad clinical spectrum ranging from nonalcoholic fatty liver to nonalcoholic steatohepatitis ...

Primary liver cancer has several well-recognized risk factors, such as HBV and HCV infection, alcohol abuse and aflatoxin. Recent studies show that nonalcoholic fatty liver disease (NAFLD), especially its aggressive form nonalcoholic steatohepatitis (NASH) is associated with an increased risk of liver cancer, mainly hepatocellular carcinoma (HCC). On the other hand, clinical and epidemiological...