Fetal heart rate extraction from the abdominal ECG is of great importance due to the information that carries in assessing appropriately the fetus well-being during pregnancy. In this paper, we describe a method to suppress the maternal signal and noise contamination to discover the fetal signal in a single-lead fetal ECG recordings. We use a locally linear phase space projection technique whic...

OBJECTIVE To determine the diagnostic value of fetal ST-segment analysis (STAN) in predicting neonatal acidosis. METHODS The STAN S21 was used to monitor singleton fetuses in labor with abnormal FHR. Physicians later reviewed tracings to identify any ST events dictating intervention. Outcome measures were umbilical artery pH< or =7.15 and pH< or =7.05 at birth. The sensitivity, specificity, P...

Obstetricians were asking the engineering support to study more extensively any technical possibility to electronically get some useful information from the whole PQRST complex of the fetal electrocardiogram (fECG) in order to identify eventual sign of fetal distress (FD). The latter should indeed be found as a more reliable information for the clinician with the potential benefit of increasing...

background: fetal dna has been found in maternal plasma. diagnosis of fetal gender using maternal plasma has been attempted in an effort to develop a new noninvasive method of prenatal diagnosis. methods: we extracted dna from plasma of 30 pregnant woman, three men, three non-pregnant women, and performed a sensitive y-pcr assay to detect circulating male fetal dna from women bearing male fetus...

OBJECTIVES RASSF1A has been described to be differentially methylated between fetal and maternal DNA and can therefore be used as a universal sex-independent marker to confirm the presence of fetal sequences in maternal plasma. However, this requires highly sensitive methods. We have previously shown that Pyrophosphorolysis-activated Polymerization (PAP) is a highly sensitive technique that can...

Fetal brain injury resulting from hypoxia and ischemia during labor remains an important cause of death and long-term disability. However, little is known about fetal brain oxygenation and hemodynamics. There are currently no satisfactory clinical techniques for fetal monitoring and there remains a need for a new method to assess brain oxygenation. Fetal near infrared spectroscopy (NIRS) is a n...

Sudden cardiac arrest is most often due to ventricular fibrillation (VF). When no cause found during diagnostic follow-up, classified as idiopathic VF. We hypothesize that subtle repolarization abnormalities may predispose VF, but cannot be detected from the 12-lead electrocardiogram (ECG). To study presence of time (RT) gradients in patients with VF using ECG and noninvasive electrocardiograph...

Fetal electrocardiogram (FECG) extraction has a vital role in medical diagnosis during pregnancy. In this paper, We Proposed a method for removal of background noise and artifacts from FECG signals using adaptive filters has been proposed. The proposed method uses adaptive noise cancellation and digital filters for FECG extraction. Proposed FECG extraction algorithm has been implemented in MATL...

Magnetocardiography (MCG) is a technique that enables the noncontact, noninvasive measurement of electrocardiographic phenomena, and fetal magnetocardiography (FMCG) is extremely useful for the analysis of fetal electrocardiographic phenomena. We have used FMCG for the diagnosis and treatment of a range of fetal arrhythmias, and to perform comparative studies of autonomic nervous system activit...