A novel neural modelling method, namely ‘eng-genes’, is proposed for complex nonlinear dynamic engineering systems. This method performs system modelling by first establishing the ‘eng-genes’ – some fundamental engineering functions from 'a priori' engineering knowledge, which are then constructed and coded into appropriate chromosome representations. Given a suitable fitness function, using ev...

In this paper, we propose a semi-parametric model for autonomous nonlinear dynamical systems and devise an estimation procedure for model fitting. This model incorporates subjectspecific effects and can be viewed as a nonlinear semi-parametric mixed effects model. We also propose a computationally efficient model selection procedure. We prove consistency of the proposed estimator under suitable...

BACKGROUND The six-minute walk test (6MWT) is commonly used to quantify exercise capacity in patients with several cardio-pulmonary diseases. Oxygen uptake ([Formula: see text]O2) kinetics during 6MWT typically follow 3 distinct phases (rest, exercise, recovery) that can be modeled by nonlinear regression. Simultaneous modeling of multiple kinetics requires nonlinear mixed models methodology. T...

Introduction Conclusions References Tables Figures ◭ ◮ ◭ ◮ Back Close Full Screen / Esc Papers published in Hydrology and Earth System Sciences Discussions are under open-access review for the journal Hydrology and Earth System Sciences Abstract Introduction Conclusions References Tables Figures ◭ ◮ ◭ ◮ Back Close Full Screen / Esc Abstract The soil hydraulic parameters for analyzing soil water...

Complex pharmacokinetic (PK) properties including nonlinear elimination were encountered by some monoclonal antibodies (mAbs), and classic compartment models sometimes failed to appropriately describe those properties. In this work, a new model was built on a comprehensive analysis of the complex elimination of mAbs. This new model was firstly utilized to fit with the single-dose plasma concent...

Complex pharmacokinetic (PK) properties including nonlinear elimination were encountered by some monoclonal antibodies (mAbs), and classic compartment models sometimes failed to appropriately describe those properties. In this work, a new model was built on a comprehensive analysis of the complex elimination of mAbs. This new model was firstly utilized to fit with the single-dose plasma concent...

Various methods have been proposed for fitting subdivision surfaces to different forms of shape data (e.g., dense meshes or point clouds), but none of these methods effectively deals with shapes with sharp features, that is, creases, darts and corners. We present an effective method for fitting a Loop subdivision surface to a dense triangle mesh with sharp features. Our contribution is a new ex...

this paper deals with the extraction of l-theanine containing aliquat 336 as a carrier and cyclohexane as solvent across bulk liquid membrane. the optimum operation condition are as follows: extraction time of 150 min, initial concentration of theanine in the feed phase is 1.8 g/l, the carrier concentration is 0.5 m, the ion of the receiving phase is 0.2 m nacl of na2hpo4-nah2po4 buffer solutio...

This research proposes a computation approach to address the evaluation of end product machining accuracy in elliptical surfaced helical pipe bending using 6dof parallel manipulator as a pipe bender. The target end product is wearable metal muscle supporters used in build-to-order welfare product manufacturing. This paper proposes a product testing model that mainly corrects the surface directi...

The aim of this study is to show the relationship of elastic large deformation between torque and torsional angle for a bar with rectangular cross section. The formula about torque and torsional angle is modified by numerical analysis and experimental verification. High order item of torsional angle is added to the traditional formula, based on different boundary condition, which was set to zer...