Introduction: Interstitial lung disease (ILD) induced end-stage fibrosis is a multiphase process that includes: 1) an initial or exposure phase; 2) an exudative phase; and 3) a final stage with one of two outcomes; a) edema clearance associated with alveolar wound healing and recovery, or b) organization of the alveolar space filling material followed by scar formation associated with loss of n...

AIM To study the expression profile of the NaPi2b protein and its localization in breast, ovarian and lung cancer cells in relation to normal tissues adjacent to tumor. METHODS Immunohistochemical analysis with monoclonal antibody MX35 was applied for investigation of NaPi2b protein expression in breast, lung and ovarian carcinomas. Intensity of NaPi2b protein expression was calculated with s...

    Many studies have been performed for treatment or prevention of pulmonary fibrosis. However, no effective treatment has been found yet. The aim of this study was to investigate the effect of grape seed extract on bleomycin-induced lung fibrosis in rat. Hydroalcoholic extract of grape seed (Vitis vinifera) was prepared using maceration method. NMRI rats weighing 250-300 g were given...

Tuberculosis is considered the main health threat in several parts of world. This ithe primary infectiousdisease causing this disease .When untreatedandundiagnosed, there ishigh mortalityrate patients.Thismethodincludes an automatic method to recognize tubersT his approach requires automated tuberculosis identification techniques reduce problematic illnesses. Extraction lung region first perfor...

A 37-year-old woman had pleuritic chest pain, dyspnea, and normal findings on chest roentgenogram. Lung scan showed markedly diminished perfusion to the right lung with a matched ventilatory defect. Further evaluation revealed a bronchogenic cyst. After resection, the lung scan was normal. To our knowledge, this is the first report of a bronchogenic cyst causing a reversible, unilateral ventila...

BACKGROUND Lung cancers develop via multiple genetic and epigenetic changes, including inactivation of tumor suppressor genes. We previously cloned human G protein-coupled receptor family C type 5A (GPRC5A), whose expression is suppressed in some human lung carcinoma cells, and its mouse homolog Gprc5a. METHODS We generated Gprc5a knockout mice by homologous recombination and studied their ph...

Connective tissue growth factor (CTGF) is a secreted protein that belongs to CCN family. The proteins in this family are implicated in various biological processes, such as angiogenesis, adhesion, migration, and apoptosis. In this study, we explored the roles of CTGF in lung tumorigenesis. The expression levels of CTGF in 58 lung cancer samples were reduced by >2 fold in 57% of the samples comp...

BACKGROUND Obesity-related diseases have been shown to affect post-lung transplantation survival. An estimated 30% of lung transplant recipients develop overweight. OBJECTIVE The aim of this study was to examine the possible determinants of large increases in weight after lung transplantation. The contribution of physical activity, food intake, and resting energy expenditure was examined in l...