The possibilities of using laser-induced fluorescence for tissue diagnostics are discussed. The tissue types investigated are malignant tumors and atherosclerotic lesions. Studies with natural autofluorescence as well as with fluorescent tumor markers are included in this paper. Fluorescence emission and decay data are presented for some tissue chromophores contributing to tissue autofluorescen...

Alkaline phosphatase activity in four strains of cultured skin fibroblasts obtained from a patient with fibrodysplasia ossificans progressiva was at the low normal range. The enzyme activity in normal fibroblasts significantly increased at late confluency. It appears that the high levels of alkaline phosphatase activity reported in biopsies of lesions are not genetically determined but are seco...

Factor XIIIa+ and CD34+ dendritic cells, believed to be subsets of monocyte/macrophages, have been identified in dermis and in dermal tumors. The purpose of this study was to determine the presence and distribution of analogous cell types in oral submucosa and oral fibro-vascular lesions. Antibodies to XIIIa, CD34, S-100 protein, and macrophage antigen (MAC 387) were tested on formalin-fixed, p...

fixed myocardial defects in both stress and rest images, could be artifactual as a result of soft tissue attenuation. to increase specificity and identify the false positive results, we used gated technique to evaluate the wall motion and wall thickening as an index to differentiate real ischemic lesions from artifactual defects. 93 patients were studied. in 46 patients (48.8%) fixed perfusion ...

Aim: Mammography and ultrasonography are helpful diagnostic methods for the detection of asymptomatic lesions prior to reduction mammoplasty operations. Preoperative radiological evaluation does not give accurate results all time. Consequently, preoperative radilological and postoperative histopathologic evaluation were used together in order to diagnose the premalignant and silent cancer foci....

Previous observations have indicated lamellated ultrastructural lesions in the myocardium of a patient treated with methylphenidate (Ritalin) hydrochloride (MPH). A causal relationship between MPH exposure and these membranous changes was tested in the myocardium of rats and mice. Following injection of varying doses of MPH for different periods, myocardial ultrastructure was examined and lesio...

Introduction: Among the different types of MS brain lesions observed by MRI, black holes are thought to be most associated with significant tissue destruction including axonal loss [1]. Black holes are usually detected as hypointense areas compared to the normal appearing white matter (NAWM) on T1-weighted (T1w) images generated by conventional turbo-spin-echo (SE) MRI sequences. Unfortunately,...

Osseous lesions of the tongue, also referred to as osseous choristomas, are benign growths of bony tissue. These lesions are not true neoplasms but rather represent growth of normal tissue at an abnormal location. Clinically, they appear as exophytic masses of the tongue, and they are treated by surgical excision. Lingual osseous choristomas are rare entities, with only 71 reported cases in the...