It has been well known that mesalazine can cause the interstitial lung disease, such as Bronchiolitis obliterans with organizing pneumonia (BOOP), Non-Specific Interstitial Pneumonia (NSIP), or eosinophilic pneumonia. 5-Aminosalicylic acid (5-ASA), mesalazine, and sulfasalazine are important drugs for treating inflammatory bowel disease. Topical products of these limited systemic absorption and...

UNLABELLED Primary Sjögren syndrome (PSS) is a chronic inflammatory autoimmune disease. Interstitial lung disease (ILD) can be an extraglandular complication. OBJECTIVE To evaluate the clinical characteristics of patients diagnosed with PSS with ILD. METHODS Multicentre cohort study with 25 patients diagnosed with PSS and ILD. Data of PSS, prognostic factors, pulmonary involvement variables...

A 56-year-old woman was admitted to our hospital for treatment of non-specific interstitial pneumonitis (NSIP). The patient started prednisone treatment, but one month later treatment with voglibose, an alpha-glucosidase inhibitor (alpha-GI), was started because of prednisone-induced diabetes mellitus. One week later, a massive volume of free air below the diaphragm was detected by a chest X-ra...

Background: Extra-articular manifestation (EAMs) definition is not clearly defined in psoriatic arthritis (PsA). Nail involvement, enthesitis, dactylitis has been widely studied however, data are needed on pulmonary involvement PsA. Objectives: We aimed to understand real-life results of lung PsA patients. Methods: From the cohort followed our outpatient clinic, patients who have requested a ch...

Background Some rheumatological diseases may involve the lungs. This is something that rheumatologist and pulmonologist must take into account in their clinical practice. Objectives To describe characteristics of a group patients with diffuse interstitial lung disease (ILD) are being followed-up Rheumatology-Pneumology monographic consultation study usefulness this consultation. Methods We revi...

In 2016, the Federal government of Nigeria under President Muhammadu Buhari established National Social Investment Program (NSIP), including Cash Transfers (CTs) to tackle poverty in country and prevent vulnerable households from falling further down line. The CTs program, known as Household Upliftment (HUP) targeted poorest poor for 6 years (2016-2022) by giving N5000 monthly “poor” across 36 ...

damage on high-resolution computed tomography despite stable lung function in cystic fibrosis. We read with great interest the report by BRASCH et al. [1] on a case of interstitial lung disease (ILD) due to a de novo heterozygous missense mutation in the surfactant protein-C gene (SFTPC), which resulted in the substitution of threonine for isoleucine in codon 73 of the propeptide of the surfact...

Background Despite a lower risk of ILD and progression in anti-centromere antibody (ACA) positive systemic sclerosis (SSc) patients, may still occur progress. Little is known regarding factors for ACA+ SSc patients to help guide screening with high-resolution computed tomography (HRCT), understudied. Objectives To determine prevalence SSc, classify radiographic patterns, evaluate rate SSc. Meth...

In the new millennium, idiopathic pulmonary fibrosis (IPF) is not what it was thought to be 20 years ago. In the past, the term was used for a heterogeneous group of interstitial lung disorders of unknown cause, after exclusion of possible exposures or associated conditions. Now IPF is more narrowly defined as a distinct clinical entity, with certain characteristic clinical, radiological and mo...