Awake craniotomy represents an essential option for surgical procedures requiring a patient’s participation in defining the extent of resection. This includes excision of epileptogenic foci, performed in patients with medically refractory epilepsy. Approximately 2 million Americans with a diagnosis of epilepsy are treated with Antiepileptic Drugs (AEDs), of these 20 percent continue to have sei...

Since the development of Deep Brain Stimulation (DBS) for Parkinson's Disease, DBS has been suggested as a treatment option for various other neurological disorders. Stimulation of deep brain structures for refractory epilepsy appears to be a safe treatment option with promising results. As research on the evaluation and optimization of DBS for refractory epilepsy may be difficult and unethical...

introduction: scattered photon is one of the main defects that degrade the quality and quantitative accuracy of nuclear medicine images. accurate estimation of scatter in projection data of spect is computationally extremely demanding for activity distribution in uniform and non-uniform dense media. methods: the objective of this paper is to develop and validate a scatter correction technique t...

Case presentation: Boy, 4 years old. Born term, cesarean for oligohydramnios, without consanguinity. Mother with hypothyroidism, maternal uncle autism, cousin epilepsy and paternal cerebral palsy. Adequate neuropsychomotor up to 2 of age. At this age, started ataxic gait, refractory epilepsy, spasticity, language loss dysphagia. Multiple hospitalizations due bronchoaspiration pneumonia. Gastros...

Focal epilepsy accounts for approximately one-half to two-thirds of new-onset epilepsy in children. Etiologies are diverse, and range from benign epilepsy syndromes with normal neuroimaging and almost certain remission to focal malformations of cortical development or hippocampal sclerosis with intractable seizures persisting lifelong. Other important etiologies in children include pre-, peri-,...

Epilepsy affects between 0.5% and 1% of the population and starts in childhood in two-thirds of patients. Approximately 30% of patients with epilepsy who are less than 18 years of age have medically refractory seizures [1, 2]. Seizures may adversely impact intellectual functioning [3-6] and therefore good seizure control is of critical importance. Compared with the mature brain, the impact of s...

Background & Objective: Psychiatric disorders constitute a large part of illness burden in patients with refractory epilepsy. A careful presurgical psychiatric assessment is now an integral part of evaluation in most centers performing surgeries for refractory epilepsy. This study was undertaken to determine the prevalence of psychiatric disorders and outcome of the psychopathology in patients ...

PURPOSE Cortico-amygdalohippocampectomy (CAH) has become an important treatment option for patients with refractory temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS); it has resulted in a 60-70% seizure remission rate and significant quality of life (QOL) improvements. Video-electroencephalography (VEEG) monitoring has been widely used in epilepsy centers for pre-surgical evaluatio...

introduction: in the current study, we compared the h-indices of web of science (wos), scopus, and gs of the iranian nuclear medicine scientists methods: full time members of two major nuclear medicine research centers of iran with more than 5 year of experience (nuclear medicine research center of mashhad university of medical sciences, and research institute for nuclear medicine of tehran uni...

introduction: in the current study, we compared the h-indices of web of science (wos), scopus, and gs of the iranian nuclear medicine scientists methods: full time members of two major nuclear medicine research centers of iran with more than 5 year of experience (nuclear medicine research center of mashhad university of medical sciences, and research institute for nuclear medicine of tehran uni...