It is in this connection that it becomes very difficult at times for the agricultural scientist and practical agriculturist to meet on common ground, for very often a popular version of scientific reasoning may appear ambiguous, and in this case it would appear better to sacrifice the facile version (since the layman can always get an interpreter to explain if he is sufficiently interested) tha...

A heterozygous SLC2A1 mutation in the severely affected child was inherited from his less severely affected mother who was mosaic for the mutation.

Although it was first described in 1989, our understanding of coenzyme Q10 (CoQ10) deficiency is only now coming of age with the recent first description of the underlying molecular defects. The diverse clinical presentations, classifiable into four major syndromes, raise the question as to whether the deficiencies are primary or secondary. Recent studies, including the one by Mollet, Rötig, an...

Subcloning of Simian virus 40 (SV40) T antigen-positive mouse-human hybrids, derived from the fusion of mouse cells deficient in thymidine kinase with SV40-transformed Lesch Nyhan fibroblasts, resulted in their segregation into T antigen-positive and negative subclones. Positive correlation between the presence of human chromosome 7 and the expression of SV40 T antigen was established in the su...

Misperceptions about politics and health can undermine public debate and distort people’s choices and behavior. Why do people hold these false or unsupported beliefs and why is it so difficult to change their minds? An emerging literature examines the difficulty of correcting false or unsupported beliefs and the reasons for this resistance, but relatively little is known about the sources of mi...

In women heterozygous for hypoxanthine guanine phosphoribosyl trasferase deficiency, the activity of this enzyme in the erythrocyte is usually normal. In a key kindred two such obligate heterozygotes were also heterozygous for glucose-6-phosphate dehydrogenase types A and B. The AB genotype was confirmed in one by assay of skin fibroblasts. Erythrocytes were exclusively of type B. These observa...