Sleep apnea is often diagnosed using an overnight sleep test called a polysomnography (PSG). Unfortunately, though it is the gold standard of sleep disorder diagnosis, a PSG is time consuming, inconvenient, and expensive. Many researchers have tried to ameliorate this problem by developing other reliable methods, such as using electrocardiography (ECG) as an observed signal source. Respiratory ...

PURPOSE To examine whether allostatic load (AL), a measure of cumulative physiologic dysregulation across biological systems, was associated with sleep apnea, insomnia, and other sleep disturbances. METHODS Data from the National Health and Nutrition Examination Survey 2005-2008 were used. AL was measured using nine biomarkers representing cardiovascular, inflammatory, and metabolic system fu...

The high incidence of blast exposure on today’s battlefield has been strongly associated with traumatic brain injuries. Anecdotal evidence of prolonged apnea following blast exposure has been observed in military personnel and is commonly reproduced in animal neurotrauma models. Animal models have shown that apnea tolerance is both dose and species-dependent; important factors include primary b...

OBJECTIVES/HYPOTHESIS The effect of the Pillar implant on mild sleep-disordered breathing (SDB) has been assessed in various studies. However, most of these were conducted among a non-Asian population at a single institution. Therefore, the aim of this study was to prospectively evaluate the efficacy of the Pillar implant in Asian patients with simple snoring and mild obstructive sleep apnea (O...

PURPOSE OF REVIEW The purpose of this article is to review the screening tools available in the preoperative clinic for patients at risk of obstructive sleep apnea. RECENT FINDINGS Obstructive sleep apnea (OSA) is the most prevalent sleep disorder. An estimated 82% of men and 92% of women with moderate-to-severe sleep apnea have not been diagnosed. Patients with undiagnosed OSA may have incre...

The relative impact of mechanical factors on pharyngeal patency in patients with obstructive sleep apnea is poorly understood. The present study was designed to evaluate parameters of the "tube law" on pharyngeal pressure-flow relationships and collapsibility in patients with obstructive sleep apnea. We developed a mathematical model that considered the collapsible segment of the pharynx to rep...

Apnea is a Greek word meaning “without wind.” Apnea, in the modern lexicon, refers to the cessation of breathing and is a reversible condition if caught early enough. Apneic events fall under one of three classifications—central, obstructive, or mixed. The event is classified as “central apnea” if the brain stops sending the signals to the chest muscles to expand, causing inhalation. This can o...

Abstract Introduction Moderate-Severe Obstructive Sleep Apnea (OSA, AHI>15) disturbs sleep through frequent bouts of apnea and is associated with daytime sleepiness. However, many individuals without moderate or severe OSA (i.e. AHI≤15) also report We propose that sleepiness may be a consequence substantial flow limitation, even in the absence overt reductions airflow (apnea/hypopnea). M...

We present 2 term newborn infants with apneic seizure originating in the occipital lobe that was diagnosed by video-EEG. One infant had ischemic infarction in the distribution of the posterior cerebral artery, extending to the cingulate gyrus. In the other infant, only transient occipital hyperechogenicity was observed by using neurosonography. In both cases, although the critical EEG discharge...

INTRODUCTION Autonomic dysfunction can alter heart rate variability and increase the incidence of arrhythmia. We analyzed the impact of continuous positive airway pressure (CPAP) on this pathophysiological phenomenon in patients with severe sleep apnea-hypopnea syndrome. METHODS Consecutive patients with recently diagnosed severe sleep apnea-hypopnea syndrome were prospectively considered for...