Obstructive sleep apnea is a common disorder in which the airway repetitively collapses during sleep; patients with sleep apnea are often inattentive and sleepy. This review discusses driving performance and automobile accidents in patients with sleep apnea. Finally, we discuss the effect of therapy upon driving performance and reported accidents in these subjects.

AIM The aim of the Danish National Database for Obstructive Sleep Apnea (NDOSA) was to evaluate the clinical quality (diagnostic, treatment, and management) for obstructive sleep apnea and obesity hypoventilation syndrome in Denmark using a real-time national database reporting to the Danish National Patient Registry. STUDY POPULATION All patients diagnosed with obstructive sleep apnea or obe...

We describe a child with sickle cell anemia and multiple ischemic infarctions who was found to have severe obstructive sleep apnea and hypoxemia, secondary to adenotonsillar enlargement. The apnea-associated hypoxemia likely contributed to the development of the strokes in this child. Moreover, because stroke in patients with sickle cell anemia, and maximal tonsillar enlargement (the most commo...

Introduction Normal Physiology during Sleep: Changes with Maturation and Development Changes in Respiration during Sleep Thoracic Mechanics Upper Airway Ventilatory Control Arousal Apnea Gas Exchange Obstructive Sleep Apnea Syndrome Epidemiology Pathophysiology Complications Evaluation Treatment Long-term Outcome Central Hypoventilation Syndromes Definition Etiology Evaluation Treatment Chronic...

BACKGROUND Postoperative delirium, a common complication in the elderly, can occur following any type of surgery and is associated with increased morbidity and mortality; it may also be associated with subsequent cognitive problems. Effective therapy for postoperative delirium remains elusive because the causative factors of delirium are likely multiple and varied. METHODS Patients 65 yr or o...

Two obese patients with sleep apnea syndrome were administered chlormadinone acetate (CMA), a synthetic progesterone, known as a potent respiratory stimulant to augment load compensation response as well as CO2 chemosensitivity. Before CMA administration, both cases showed normal chemosensitivity of hypoxic and hypercapnic ventilatory responses (HVR and HCVR) at daytime, although marked oxygen ...

Obstructive sleep apnea should be suspected in patients who are overweight snore loudly, and have chronic daytime sleepiness. The diagnosis of sleep apnea may be confirmed by sleep laboratory studies. Patients' symptoms and the frequency of respiratory events on laboratory testing are important factors in determining the severity of disease. In patients with mild sleep apnea, conservative treat...

KEY TERMS I. Functional Anatomy and Physiology of Sleep A. Neurocontrol of Sleep II. Upper Airway Anatomy and Sleep A. Oropharynx III. Stages of Sleep A. Nonrapid Eye Movement B. Rapid Eye Movement IV. Sleep Disorders A. Obstructive Sleep Apnea B. Central Sleep Apnea 1. Children with Central Sleep Apnea C. Mixed Sleep Apnea V. Cardiovascular Effects of Untreated Sleep-Disordered Breathing A. Ce...

INTRODUCTION Obstructive sleep apnea occurs by recurrent collapse of the upper airway during sleep, resulting in total (apnea) or partial (hypopnea) reduction of the airflow and has intimate relation with changes in the upper airway. Cone Beam CT allows the analysis of the upper airway and its volume by three-dimensional reconstruction. OBJECTIVE To evaluate a possible correlation between the...