Pityriasis rubra pilaris (PRP) is a rare chronic inflammatory papulosquamous skin disease. Its clinical presentation and evolution is very variable. The most frequent clinical features are follicular papules, progressing to yellow-orange erythroderma with round small areas of normal skin and the well-demarcated palmoplantar keratoderma. Actually, six different types of PRP have been described b...

Background: Fumaric acid esters (FAE) have been used as a drug since 1959. The therapeutic preparation containing FAE has been one of the prominent drugs used for the systemic treatment of psoriasis since 1994 in Germany. FAE have been used in the treatment of sarcoidosis, granuloma annulare, necrobiosis lipoidica, cheilitis granulomatosa, annular elastotic giant cell granuloma, malignant melan...

Pityriasis rubra pilaris (PRP) is an uncommon papulosquamous inflammatory dermatosis of unclear aetiology. Its most remarkable clinical findings are palmoplantar hyperkeratosis, orange-red scaling plaques and hyperkeratotic follicular papules. Its extension may vary from localised subtypes to generalised skin involvement with well-demarcated areas of spared skin ("islands of sparing") to erythr...

CLL: chronic lymphocytic leukemia PR: pityriasis rosea EGFR: epidermal growth factor receptor PDGFR: platelet-derived growth factor receptor I brutinib, a Bruton tyrosine kinase inhibitor, is a new oral agent approved for the treatment of chronic lymphocytic leukemia (CLL). Ibrutinib is well-tolerated, with the majority of its adverse events within grade 1 or 2 severity. The most common nonhema...

BACKGROUND Pityriasis rosea is an acute inflamatory skin disease that the etiology is unknown but some viral agents like human herpes virus-6 and 7 and drugs are suspected. CASE REPORT A-58-year-old man with chronic hepatitis C was being followed up in our hospital. Pegylated interferon (PEG-IFN) alfa-2b (100 μg per week) and ribavirin (1000 mg/day) was started. In the third month of this tre...

Potential inhibitory effect of Citrus lemon (lemon) and Citrus sinensis (orange) on lipophilic, yeast like fungus, Malassezia furfur which causes Pityriasis versicolor, chronic superficial fungal disease of the skin have been studied by using two different methods: disc diffusion and microdilution methods. In screening of lemon and orange oil by disc diffusion method, the diameter of inhibition...

The present study aim to evaluate the potential inhibitory effect of Curcuma longa (turmeric) oil on lipophilic, yeast like fungus Malassezia furfur which causes Pityriasis versicolor disease, a common superficial fungal skin disease. The antifungal activity of turmeric oil was screened by using disc diffusion method and microdilution method. Results indicated that, in screening of turmeric oil...

Background: Pityriasis rosea is an inflammatory skin disorder with a known response to erythromycin. Considering similarities between erythromycin and azithromycin and lesser adverse effects of the latter, in a pilot study, we gave azithromycin to seven patients with pityriasis rosea and observed a noticeable improvement. The aim of this study was to evaluate the efficacy of azithromycin ...

Background: Pityriasis rosea is an acute, inflammatory and self-limited disease, which is characterized by a primary scaly plaque (Herald patch) followed by a generalized, symmetrical papulosqumous eruption (Mostly on trunk and proximal extremities). Objective: To determine the efficacy of erythromycin in the treatment of patients with pityriasis rosea. Patients and Methods: In this doubl...

Pityriasis Amiantacea, also known as pseudotinea amiantacea, is a clinical syndrome which affects the scalp, having a reaction pattern reported to occur in several inflammatory dermatoses. The authors seek to establish the correlation between its clinical, dermoscopic and light microscopy features through the analysis of scale- encrusted hair tufts submitted to histological processing.