[This corrects the article on p. 83 in vol. 5, PMID: 28983483.].

Commonly, in accordance with a given risk-function of hypothesis testing, investigators try to derive an optimal property of a test. This paper demonstrates that criteria for which a given test is optimal can be declared by the structure of this test, and hence almost any reasonable test is optimal. In order to establish this conclusion, the principle idea of the fundamental lemma of Neyman and...

Bernardino Ramazzini was a renowned physician and a prolific writer, born in Capri in 1633. He is considered the father of occupational medicine for having written the first paper on workers' diseases (De morbis artificum diatriba). His Treaty on Workers' diseases included 53 different professions, one particular and specific method of analysis, and a methodological proposal to prevent these di...

BACKGROUND To assess the effectiveness (change in knowledge and skills measured by the Fresno test) of a short course in Evidence Based Practice (EBP) carried out in a group of family medicine residents METHODS Before-after study. Participants' were 152 Family Medicine residents in their second year of the training programme. Settings were Primary Care Teaching Units in Catalonia. Interventio...

The aim of Personalized Medicine in disease treatment and prevention is to take account of the individual variability in genes, environment and lifestyle for each person. This approach is applied to certain tumours but is still not common for most diseases. On June 18, 2015 the TEDD network (Tissue Engineering for Drug Development and Substance Testing) invited a total of 130 academic and indus...