By taking advantage of the intrinsic fluorescence of ochratoxin A (OTA), we present a fluorescence anisotropy approach for rapid analysis of the interactions between OTA and aptamers. The specific binding of OTA with a 36-mer aptamer can induce increased fluorescence anisotropy (FA) of OTA as the result of the freedom restriction of OTA and the increase of molecular volume, and the maximum FA c...

Ochratoxin A (OTA) is among the most important mycotoxins, and the International Agency for Research on Cancer (IARC) classifies it as possibly carcinogenic to humans (group 2B). A total of 121 samples of dried fruits from the central zone of Iran were analyzed for OTA by enzyme linked immunosorbent assay (ELISA) technique. The recovery percentages of OTA in spiked dried fruit samples at concen...

BACKGROUND Ochratoxin A (OTA) is the main mycotoxin found in grapes, wines and grape juices and is considered one of the most harmful contaminants to human health. In this study, samples of tropical wines and grape juices from different grape varieties grown in Brazil were analysed for their OTA content by high-performance liquid chromatography. RESULTS The detection and quantification limits...

Ochratoxin A (OTA) is a fungal metabolite dangerous for human and animal health due to its nephrotoxic, immunotoxic, mutagenic, teratogenic and carcinogenic effects, classified by the International Agency for Research on Cancer in group 2B, possible human carcinogen. This toxin has been stated as a wine contaminant since 1996. The aim of this study was to develop a conceptual model for the dyna...

Since ochratoxin A (OTA) was discovered, it has been ubiquitous as a natural contaminant of moldy food and feed. The multiple toxic effects of OTA are a real threat for human beings and animal health. For example, OTA can cause porcine nephropathy but can also damage poultries. Humans exposed to OTA can develop (notably by inhalation in the development of acute renal failure within 24 h) a rang...

A total of 93 Portuguese grape samples destined for wine production were examined for the presence of ochratoxin A (OTA) and the OTA producing fungi Aspergillus carbonarius and A. niger aggregate. Samples came from 11 vineyards from four winemaking regions in the North and South of the Portuguese mainland, during the harvest seasons of 2001, 2002 and 2003. Grapes were examined at 3 maturation s...

Ochratoxin A (OTA) is a very important mycotoxin, and its research is focused right now on the new findings of OTA, like being a complete carcinogen, information about OTA producers and new exposure sources of OTA. Citrinin (CIT) is another important mycotoxin, too, and its research turns towards nephrotoxicity. Both additive and synergistic effects have been described in combination with OTA. ...

Aim: The aim of this study was to check the current status of OTA contamination of the Serbian pork and chicken meat in naturally exposed animals which are part of chain production. The knowledge of these factors, their importance and significance, can be used as a tool from the food safety point of view to predict if OTA content in pork and chicken tissues poses a risk to human health and dele...

A class of RC-OTA hysteretic-chaotic oscillators has been previously reported using electronics; therefore, hysteresis is realized by an electronic circuit. To obtain a mathematical model of this RC-OTA chaotic-electronic device, hysteresis modeling turns an important issue. Here, we develop a new mathematical hysteretic model proposing a new jounce-chaotic oscillator. Chaosity test is proved u...

A class of RC-OTA hysteretic-chaotic generators has been proposed from the electronics point of view. Hysteresis is captured by an electronic realization. To extend its applicability, hysteretic mathematical modeling is an important issue. Here, a new hysteretic model is proposed. With this model, we realized a well known hysteretic-chaotic attractor using Simnon.