Ocuserts are the new drug delivery systems which are designed in such a way that they release the drug at predetermined and predictable rates thus eliminating. Ocular Drug Delivery System Ocuserts authorSTREAM Presentation.Ocuserts Containing Ciprofloxacin β CD Complex. Such developed ocuserts were o pastor animarum pdf subjected to invitro characterization and o sorriso das estrelas pdf evalua...

although the conventional therapies have obviously improved the conditions of patients with cancer, some mechanisms of resistance have led scientists to use alternative agents that can penetrate in most solid tumors. furthermore, the success of cancer therapies depends on limiting the uptake of toxins to normal tissues and their selectivity to malignant cells. the involvement of natural and gen...

Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce enzyme degradation, prolong the circulation time of various drugs. SLNs applied in oral, parenteral, transdermal, intranasal, ocular, pulmonary drug delivery different drugs, with enhanced safety, bioavailability, overall th...

BACKGROUND The eye's unique anatomy and its physiological and anatomical barriers can limit effective drug delivery into the eye. METHODS An in vivo study was designed to determine the effectiveness and safety of ultrasound application in enhancing drug delivery in a rabbit model. Permeability of a steroid ophthalmic drug, dexamethasone sodium phosphate, was investigated in ultrasound- and sh...

PURPOSE To evaluate the effect of drug ionization on the ocular hypotensive activity of topical carbonic anhydrase inhibitors. METHODS Ocular normotensive New Zealand albino and ocular hypertensive Dutch Belted pigmented rabbits were used. Tonometric intraocular pressure levels were taken after topical application of 50 microliters of drug (at various concentrations and pH values) to one eye ...

Controlled and sustained delivery of ophthalmic drugs continues to remain a major focus area in the field of pharmaceutical drug delivery with the emergence of new, more potent drugs and biological response modifiers that may also have very short biological half-lives. The present review was conducted on drug delivery to the ocular route. Polymers with suitable rheological properties can facili...

International Journal of Pharmaceutical Sciences Review and Research Available online at www.globalresearchonline.net © Copyright protected. Unauthorised republication, reproduction, distribution, dissemination and copying of this document in whole or in part is strictly prohibited. © Copyright protected. Unauthorised republication, reproduction, distribution, 61 S. Nagalakshmi*, N. Damodharan,...

It is well known that ocular bioavailability after topical instillation is extremely low compared with the other administration including oral administration, transdermal application, vitreous injection, and implantable delivery. The ocular bioavailability is also affected by a variety of pharmaceutical factors such as formulation viscosity and the particle size of suspension, and so on. In spi...