Acute myopia following use of some drugs is a relatively rare condition. Topiramate prescribed for seizure prophylaxis is one of these drugs. In this paper a case of acute transient myopia after taking topiramate is reported. The reported patient is a 28-year old woman who had no history of any eye disease. Following consumption of topiramate pill for one week, she had found blurred vision ...

INTRODUCTION T oxoplasmosis is caused by the intracellular protozoan Toxoplasma gondii , that infects up to a third of the world’s population. Infections may be acquired congenitally or through the ingestion or handling of undercooked or raw infected meat, contaminated vegetables or water. The disease is asymptomatic in many immunocompetent hosts, however ocular lesions may be present in up to ...

PURPOSE Composed of sheets of cells detached from the underlying conjunctiva, conjunctival epithelial flap (CEF) is a recently reported phenomenon associated with contact lens wear with potential consequences for ocular health. Although CEF is generally asymptomatic, it is not known to what extent it might increase the longer-term risk of discomfort, inflammatory response, or infection. In this...

The effect of local and systemic injections of mesenchymal stem cells derived from adipose tissue (AD-MSC) into rabbit models of corneal allograft rejection with either normal-risk or high-risk vascularized corneal beds was investigated. The models we present in this study are more similar to human corneal transplants than previously reported murine models. Our aim was to prevent transplant rej...

PURPOSE Ocular trauma is common in civilian and military populations. Commotio retinae involves acute disruption of photoreceptor outer segments after blunt ocular trauma, with subsequent photoreceptor apoptosis causing permanent visual impairment. The mechanisms of photoreceptor death in commotio retinae have not previously been described, although caspase-dependent death is important in other...

a 65–yrs-old man referred for an ocular discomfort and red eye. the clinical diagnosis was leech in the left eye and its species confirmed as being limnatis nilotica . ocular leech infestation should be considered in patients with a history of swimming or washing their face in streams and lakes. attention should also be given to ocular leech infestation in the differential diagnosis of ocular t...

Purpose: Commotio retinae (CR) involves photoreceptor outer segment disruption after blunt ocular trauma and occurs in 0.4% of civilian and 19% of military eye injuries. Photoreceptor degeneration permanently reduces vision in 26% of patients with macula involvement. In animal models of CR, photoreceptors die by both necrosis and apoptosis. Apoptotic mechanisms in CR have not been described. We...

CONTEXT Whether immunosuppressive treatment adversely affects survival is unclear. OBJECTIVE To assess whether immunosuppressive drugs increase mortality. DESIGN Retrospective cohort study evaluating overall and cancer mortality in relation to immunosuppressive drug exposure among patients with ocular inflammatory diseases. Demographic, clinical, and treatment data derived from medical reco...

PURPOSE To analyze the clinical features, treatment outcomes, and prognostic factors associated with lymphoproliferative lesions of the ocular adnexa in a Korean population. METHODS Data from 69 patients treated for adnexal lymphoproliferative disease in the 12-year period from 1991 to 2002 were retrospectively evaluated. RESULTS The 69 patients had a median age of 46 years (range, 15-73 ye...

IMPORTANCE This study evaluates the longevity of Descemet membrane endothelial keratoplasty (DMEK) grafts in terms of endothelial survival and endothelial failure. OBJECTIVE To determine endothelial survival and its association with the indication for surgery and/or partial graft detachment in DMEK. DESIGN, SETTING, AND PARTICIPANTS Retrospective cross-sectional study of data collected from...