Background: Patients with oculocutaneous albinism (OCA) are prone to develop skin cancers. Aim and Objectives: To analyze reports of skin cancers in albinos published in the English and the Japanese literature in order to prepare guidelines for the successful management of skin cancer in albinos. Methods and Materials: We searched on PubMed, Web of Knowledge for English literature, and Ichushi-...

BACKGROUND The social reality of the albino needs to be more studied in Brazil, as myths and social segregation regarding this illness are likely to be found in the country, with psychosocial and medical implications. OBJECTIVE As this subject has not been referenced in previous scientific articles in Brazil, this research intends to evaluate the quality of life of the albinos that treated at...

Hypopigmentation disorders that are associated with immunodeficiency feature both partial albinism of hair, skin and eyes together with leukocyte defects. These disorders include Chediak Higashi (CHS), Griscelli (GS), Hermansky-Pudlak (HPS) and MAPBP-interacting protein deficiency syndromes. These are heterogeneous autosomal recessive conditions in which the causal genes encode proteins with sp...

This study was conducted to evaluate possible bystander effects induced by the model chemical 6-propyl-2-thiouracil (PTU) on melanin synthesis. Zebrafish (Danio rerio) embryos were treated with PTU by either microinjection exposure, via waterborne exposure or indirectly through bystander exposure. Melanin content, related mRNA and protein expression were examined at the end of exposure (36 h po...

21 Previously we reported electrophysiological evidence for a role for the anterior thalamic 22 nucleus (ATN) in human memory formation (Sweeney-Reed et al. 2014). Theta-gamma 23 cross-frequency coupling (CFC) predicted successful memory formation, with the 24 involvement of gamma oscillations suggesting memory-relevant local processing in the ATN. 25 The importance of the theta frequency range...

The current state of the machine translation system STYLUS is described. The system can produce smooth and accurate translation for more than 80% of source text in the domain chosen. The modular structure of the dictionaries gives the possibility of customising the system to personal needs. The grammar employed is based on ATN-like formalism.

At the start of my career, I had the good fortune of working with Ron Kaplan on Bill Woods’ Lunar system (Woods et al., 1972). One day, in talking with Ron, I marvelled to him over the range of syntactic constructions I was able to implement in Lunar’s ATN grammar formalism. Ron replied was that you could implement anything in an ATN: the point was, rather, to identify the minimal machinery req...