نتایج جستجو برای: one locus mismatch

تعداد نتایج: 2075455  

There are two significant goals in teleoperation systems: Stability and performance. This paper introduces an LMI-based robust control method for bilateral transparent teleoperation systems in presence of model mismatch. The uncertainties in time delay in communication channel, task environment and model parameters of master-slave systems is called model mismatch. The time delay in communicatio...

Journal: :IEICE Transactions 2014
Keitaro Ue Kunihiro Fujiyoshi

Recently most of integrated circuit chips are made from monolithic IC, which can be manufactured at low cost. In monolithic IC, absolute error which is proportion of the difference of actual value to the designed value of each element is large (several tens of percentages), but the maximum difference of the absolute error of devices on a chip, is small (a few percentages). So it is suitable to ...

2012
Michele Cristóvão Evangelos Sisamakis Manju M. Hingorani Andreas D. Marx Caroline P. Jung Paul J. Rothwell Claus A. M. Seidel Peter Friedhoff

Mismatch repair (MMR) corrects replication errors such as mismatched bases and loops in DNA. The evolutionarily conserved dimeric MMR protein MutS recognizes mismatches by stacking a phenylalanine of one subunit against one base of the mismatched pair. In all crystal structures of G:T mismatch-bound MutS, phenylalanine is stacked against thymine. To explore whether these structures reflect dire...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1998
M C Earley G F Crouse

In most organisms, the mismatch repair (MMR) system plays an important role in substantially lowering mutation rates and blocking recombination between nonidentical sequences. In Saccharomyces cerevisiae, the products of three genes homologous to Escherichia coli mutS-MSH2, MSH3, and MSH6-function in MMR by recognizing mispaired bases. To determine the effect of MMR on single-base pair mismatch...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Tim Arlow Kristan Scott Aubrey Wagenseller Alison Gammie

MSH2 is required for DNA mismatch repair recognition in eukaryotes. Deleterious mutations in human MSH2 account for approximately half of the alleles associated with a common hereditary cancer syndrome. Previously, we characterized clinically identified MSH2 missense mutations, using yeast as a model system, and found that the most common cause of defective DNA mismatch repair was low levels of...

Journal: :Journal of Biological Chemistry 2015

2016
Dinglin Zhang Danfeng Chen Liaoran Cao Guohui Li Hong Cheng Sung Key Jang

Incorrect protein translation, caused by codon mismatch, is an important problem of living cells. In this work, a computational model was introduced to quantify the effects of codon mismatch and the model was used to study the protein translation of Saccharomyces cerevisiae. According to simulation results, the probability of codon mismatch will increase when the supply of amino acids is unbala...

2005
Robert Shimer

This paper develops a dynamic model of mismatch. Workers and jobs are randomly assigned to labor markets. Each labor market clears at each instant but some have more workers than jobs, hence unemployment, and some have more jobs than workers, hence vacancies. As workers and jobs move between labor markets, some unemployed workers find vacant jobs and some employed workers lose or leave their jo...

Journal: :Journal of medical genetics 2000
C Vaurs-Barrière F Penault-Llorca V Laplace-Marieze N Presneau C M Maugard M Fiche A Hardouin Y J Bignon

EDITOR—BRCA1 is one of the major breast and ovarian cancer susceptibility genes. Many studies have suggested that the BRCA1 protein is multifunctional. Notably, it may play a role in DNA repair, especially in double strand break (DSB) DNA repair by homologous recombination because (1) BRCA1 acts in association with Rad51, 2 (2) DNA damage induces its phosphorylation and delocalisation from nucl...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید