نتایج جستجو برای: opioid drugs
تعداد نتایج: 252464 فیلتر نتایج به سال:
We are pleased to present a select number of abstracts from the proceedings of the CSRT Annual Education Conference. Held in Ottawa, Ontario, May 26 to 28, 2016, this conference included topics delivered by international, national and regional individuals with expertise in various areas of respiratory therapy practice, including quality assurance, patient safety, evidence-based practice, patien...
Introduction Fixed drug eruption (FDE) is a pattern of a drug-induced skin reaction. It is characterized by skin erythematous plaques that recur at the same site each time the drug is administered. Several drugs have been associated to such cutaneous reaction, including, anticonvulsant agents, sulfonamides, non opioid analgesics and tetracyclines. Non steroidal anti-inflammatory drugs (NSAIDs) ...
The purpose of this study was to identify co-morbidity in a national sample (N=1408) of males and females entering treatment for opioid abuse. Our sample was primarily white, lived in small urban, suburban or rural locations (80%), and was well-educated. Chronic pain was a symptomatic feature in over 60% of all subjects. Furthermore, 79% of male and 85% of female prescription opioid abusers ind...
Opioid drugs produce their pharmacological effects by activating inhibitory guanine nucleotide-binding regulatory protein-linked mu, delta, and kappa opioid receptors. One major effector for these receptors is adenylyl cyclase, which is inhibited upon receptor activation. However, little is known about which of the ten known forms of adenylyl cyclase are involved in mediating opioid actions. He...
Pain is sensed by the activation of painful nociceptors in periphery or pain mediators, such as bradykinin, serotonin, histamine, and prostaglandin, released from damaged tissue, afferent transmission to medulla spinalis, transmission stages high centers over dorsal horn. Pain, which was seen only a warning sign past, now accepted phenomenon itself that needs be treated search for new, stronge...
Background:Naltrexone is a competitive opioid receptor antagonist blocking the euphoric effects of exogenous opioids. When used concomitantly with opioids, naltrexone causes severe withdrawal symptoms.The main aim of the study is to determine the symptomatology and outcome of patients who consumed naltrexone in conjunction with an opioid substance. Methods:This cross-sectional study was perf...
Chronic pain patients receiving opioid drugs are at risk for opioid-induced hyperalgesia (OIH), wherein opioid pain medication leads to a paradoxical pain state. OIH involves central sensitization of primary and secondary afferent neurons in the dorsal horn and dorsal root ganglion, similar to neuropathic pain. Gabapentin, a gamma-aminobutyric acid (GABA) analog anticonvulsant used to treat neu...
People who inject drugs are more likely to be HIV positive and to have a mental disorder than the general population. We explore how the detection and treatment of mental illness among people who are injecting drugs are essential to primary and secondary prevention of HIV infection in this population. Aside from opioid addiction, few studies have been conducted on the links between mental disor...
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