Poliovirus transmission has been eliminated in most of the world through the use of inactivated poliovirus vaccine (IPV) and live, attenuated oral poliovirus vaccine (OPV). In the United States, use of OPV was discontinued by the year 2000 because of the potential for vaccine-associated paralytic polio (VAPP); an average of eight cases were reported each year in the United States during 1980-20...

In INterdomain Ingress Traffic Engineering (INITE), a “target” Autonomous System (AS) aims to control the ingress link at which the traffic of one or more upstream source networks enters that AS. In practice, ISPs often manipulate, mostly in a trial-and-error manner, the length of the AS-Path attribute of upstream routes through a simple technique known as prepending (or padding). In this paper...

BACKGROUND Identification of mechanisms that limit poliovirus replication is crucial for informing decisions aimed at global polio eradication. Studies of mucosal immunity induced by oral poliovirus (OPV) or inactivated poliovirus (IPV) vaccines and mixed schedules thereof will determine the effectiveness of different vaccine strategies to block virus shedding. We used samples from a clinical t...

It is hoped, and widely expected, that early in the next century the wild-type polio virus will be declared extinct as a result of an eradication programme started in 1988 by the World Health Assembly using live attenuated trivalent oral (Sabin) polio vaccine (OPV). This potential achievement is reminiscent of the successful eradication of smallpox in 1977, but there are important diVerences. M...

Capacitance measurements, widely used to characterize numerous semiconductor properties, have been recently adopted to characterize organic photovoltaic (OPV) devices. It is known that certain challenges are associated with capacitance measurements. Of upmost importance is the employment of a proper measurement model (series or parallel). Owing to larger capacitive impedances and low series res...

Multiresponsive materials that display predefined photoluminescence color changes upon exposure to different stimuli are attractive candidates for advanced sensing schemes. Herein, we report a cyano-substituted oligo(p-phenylene vinylene) (cyano-OPV) derivative that forms five different solvent-free solid-state molecular assemblies, luminescence properties of which change upon thermal and mecha...

The authors report that the poly 3-hexylthiophene-2,5-diyl P3HT nanogratings shaped by nanoimprint lithography show enhanced hole mobility and strong anisotropy of conductance due to nanoimprint-induced three-dimensional polymer chain alignment. Field effect transistors were fabricated using these nanogratings and device measurements show a hole mobility of 0.03 cm2 /V s along the grating direc...

We demonstrate the fabrication of poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate) (PEDOT:PSS) nanogratings by a dehydration-assisted nanoimprint lithographic technique. Dehydration of PEDOT:PSS increases its cohesion to protect the nanostructures formed by nanoimprinting during demolding, resulting in the formation of high quality nanogratings of 60 nm in height, 70 nm in width and 70 n...

Global polio eradication is closer than ever. Replacement of the live attenuated oral poliovirus vaccine (OPV) by inactivated poliovirus vaccine (IPV) is recommended to achieve complete eradication. Limited global production capacity and relatively high IPV costs compared to OPV spur the need for improved polio vaccines. The target product profile of these vaccines includes not only dose sparin...