OBJECTIVE Early-stage oral or oropharyngeal carcinomas are often treated with surgical resection. Resulting wounds that are too large for primary closure can be covered with skin grafts or patches made from various biomaterials. Recently, polyglycolic acid sheets have been used for this purpose. METHODS We treated six patients with large wounds resulting from the resection of oral or orophary...

BACKGROUND To determine in a large series of surgical biopsies, the frequency of various histologic types of primary solid malignant neoplasms in males and females in different age groups. METHODS A retrospective study of 20,000 consecutive surgical biopsies reposted in the section of histopathology, AKU in 2004. RESULTS Malignant neoplasms are commonest in the fifth and sixth decades of li...

Case series Oral manifestations of HIV disease are broadly classified as “strongly associated with HIV”, “less commonly associated with HIV” and “can be seen in HIV infection”. Malignancies reported in HIV infection include Kaposi’s sarcoma, Non-Hodgkin’s lymphoma and squamous cell carcinoma of the oral cavity. At our RagasYRG CARE center, in a cohort of 5760 cases which were screened, 6 patien...

BACKGROUND The association between nodal ratio and survival in oral cavity carcinomas has recently been proposed, but no prospective evaluations exist. METHODS We sought to determine, using an institutional database, whether nodal ratio impacts survival in node-positive oral cavity squamous cell carcinoma. RESULTS Between 1994 and 2004, 143 new diagnoses of N(1-2) squamous cell carcinoma of...

INTRODUCTION Recent evidence suggests that the local renin-angiotensin system has been implicated in various malignancies. The mitochondrial assembly receptor is a newly identified receptor for angiotensin peptides, angiotensin-(1-7), and has an important role in the renin-angiotensin system. However, the role of the mitochondrial assembly receptor in the prognosis of cancer patients remains un...

Mucositis of the oral cavity and pharynx is a major dose-limiting factor in the application of radiotherapy (RT) to patients with head and neck cancer. Therefore, we evaluated the wound healing effect of human recombinant epidermal growth factor (rhEGF) in head and neck cancer and lymphoma patients with irradiation (with or without combined chemotherapy-induced oral mucositis). Patients at Asan...

BACKGROUND An increasing incidence of oral carcinoma among young adults has been reported in the U.S. and Europe. Although the association between human papillomavirus infection and tonsillar carcinoma is now well established, to the authors' knowledge little is known about incidence trends in tonsillar carcinoma among younger adults. The objective of the current study was to explore the trends...

OBJECTIVE To evaluate the value of sentinel lymph node biopsy in diagnosis of cervical metastasis in patients with early oral squamous cell carcinoma. METHODS Cochrane library, evidence-based medicine (EBM), PubMed, China national knowledge internet (CNKI) were searched for 2001 - 2011 literatures on sentinel lymph node biopsy in patients with oral squamous cell carcinoma as early diagnosis o...