AIMS To characterize the pharmacokinetics of fumarates in healthy subjects. METHODS Ten subjects received a single fumarate tablet (containing 120 mg of dimethylfumarate and 95 mg of calcium-monoethylfumarate) in the fasted state and after a standardized breakfast in randomized order. Prior to and at fixed intervals after the dose, blood samples were drawn and the concentrations of monomethyl...

BACKGROUND AND AIM: National oral health knowledge, attitude, and practice (KAP) data among 12-year-old children need nation-wide programs to help promote oral health. In most countries, oral epidemiologic data are collected by self-administered structured questionnaires. The aim of this study was to undertake a systematic review of the existing literature about questionnaires used for analyzin...

BACKGROUND Inequality in oral health is a major challenge. Oral diseases and their risk factors accumulate throughout life. The objective of this cross-sectional study was to examine the association of longest job with oral health status and oral health behavior among older Japanese. METHODS Subjects were a total of 23,191 (11,310 males and 11,881 females) community-dwelling individuals aged ...

Abstract Exercising and eating healthy are not just an individual choice, but influenced by the social environment. Family members, friends or neighbors influence (un)healthy choices individuals make, yet little is known about other important contacts: colleagues. Many people spend at least 8 hours a day work, mostly surrounded same As third of daily calories consumed in workplace lot time spen...

Fifteen broiler chickens (COBB 400) of 42 days of age weighing 1.8 to 2.0 kg were equally divided into 3 groups, each consisting of 5 birds. Hepatopathy was induced by oral administration of paracetamol while nephropathy was induced by intravenous administration of uranyl nitrate. Kinetic study was investigated in healthy, hepatopathic and nephropathic birds following single oral administration...