background: melon (cucumis melo) allergy is one of the most common food allergies, characterized by oral allergy syndrome. to date, two allergen molecules, cuc m 1 and cuc m 2, have been fully characterized in melon pulp, but there are few reports about the molecular characteristics of cuc m 3. methods:the cuc m 3 cdna has been characterized by rapid amplification of cdna ends (race), which rev...

background and objective: enterohemorrhagic escherichia coli (ehec) o157:h7 is an important enteric pathogen in human causing bloody or nonbloody diarrhea, which may be complicated by hemolytic uremic syndrome (hus). cattle are an important reservoir of ehec. this research aims at vaccination with a divalent chimer protein composed of espa 120 and intimin 282 and its preventive effect of ehec o...

Despite the fact that the majority of human pathogens are transmitted across mucosal surfaces, including the oral mucosae, oral immunity is poorly understood. Furthermore, because the normal flora of the oral cavity is vast and significantly diverse, host immunity must balance a complex system of tolerance and pathogen recognition. Due to the rapid recognition and response to pathogens, the inn...

Fungi belonging to Candida genus, especially C. albicans play an important role in microflora of oral cavity. Microbial colonisation process taking place within oral cavity is inseparably related to formation of multispecies biofilm, i.e. dental and denture plaque. A mature fungal biofilm is a heterogeneous three-dimensional dense conglomeration of mixture of different morphological forms: blas...

Candida is a major human fungal pathogen causing infectious conditions predominantly in the elderly and immunocompromised hosts. Although Candida resides as a member of the oral indigenous microbiota in symbiosis, some circumstances may cause microbial imbalance leading to dysbiosis and resultant oral candidiasis. Therefore, oral microbial symbiosis that suppresses the overgrowth of Candida is ...

ObjectiveThe objective of this study is to compare the microbiome healthy peri-implant sulcus (C) and peri-implantitis (U) from same patient analyze difference in composition.Materials methodsDNA samples subgingival biofilms 10 C (control group) U (uncontrolled sites were sent Microbiome Center Korea Research Institute Biomedical Science analyzed using 16s rRNA gene amplification sequencing (Mi...

Mitis-group streptococci are ubiquitous oral commensals that can promote polybacterial biofilm virulence. Using a novel murine oral mucosal co-infection model we sought to determine for the first time whether these organisms promote the virulence of C. albicans mucosal biofilms in oropharyngeal infection and explored mechanisms of pathogenic synergy. We found that Streptococcus oralis colonizat...

Chewing gum producing companies have claimed publicly that their product helps fight oral diseases. But, these companies have not publicly shown what effect their product has on the oral flora. Specifically they do not mention the effect on Streptococcus mutans, bacteria known to cause some oral diseases. This study was an in vitro study on the effects of the chewing gums Trident® and Orbit® on...

Feline immunodeficiency virus (FIV) is the feline analogue of human immunodeficiency virus (HIV) and features many hallmarks of HIV infection and pathogenesis, including the development of concurrent oral lesions. While HIV is typically transmitted via parenteral transmucosal contact, recent studies prove that oral transmission can occur, and that saliva from infected individuals contains signi...

the purpose of this study was to examine the evolution of antimicrobial activity of flower extract of hibiscus sabdariffal against antibiotic-resistant escherichia coli and staphylococcus aureus that isolates from the urinary tract infection by microtiterplate method. all 42 strains 30 e.coli and 12 s. aureus isolated from urine culture of hospitalized patients in zabol ( zabol, south-eastern i...