Methods Twenty-eight consecutive patients (22 girls) who presented to our outpatient pediatric rheumatology clinic and fulfilled the ACR criteria of fibromyalgia were included in this study. All patients underwent a rheumatologic examination performed by a pediatric rheumatologist, and an orofacial examination performed by a single dentist at the same data. The patients were interviewed accordi...

Introduction: Cognitive impairment is commonly associated with pain. The modulatory role of orexin 1 receptor (OX1R) in pain pathways as well as learning and memory processes is reported in several studies. The current study was designed to investigate the possible role of CA1-hippocampal OX1R on spatial learning and memory of rats following capsaicin-induced orofacial pain. Methods: Orofacial...

BACKGROUND The daily life of patients suffering from orofacial pain is considerably impaired as compared to healthy subjects. The aim of this study was to investigate the influence of different categories of orofacial pain on the habitual life of adult individuals. METHODS Seven hundred eighty-one individuals with orofacial pain were recruited from an initial sample of 1,058 patients. All the...

Chronic orofacial pain is a symptom associated with a wide range of neuropathic, neurovascular, idiopathic, and myofascial conditions that affect a significant proportion of the population. While the collective impact of the subset of the orofacial pain disorders involving neurogenic and idiopathic mechanisms is substantial, some of these are relatively uncommon. Hence, patients with these diso...

BACKGROUND Patients with an orofacial pain history appear to be more susceptible to occlusal interference pain in dental practice for unknown reasons. Pain memory has a critical function in subsequent pain perception. This study aims to explore whether orofacial pain memory could affect the masticatory muscle pain perception for occlusal interference. METHODS Cross-injection of 2% carrageenan...