Psychometric function plots the percentage of the correct responses among an entire pool of responses (cumulative probability) in a psychophysical task versus the amount of change in an independent variable. These changes in the independent variable are made with reference to a constant initial value. If this initial value is altered, the psychometric function will change according to Weber’s l...

The statistics of generalized F tests are quotients of linear combinations of independent chi-squares. Given a parameter, θ, for which we have a quadratic unbiased estimator, θ̃, the test statistic, for the hypothesis of nullity of that parameter, is the quotient of the positive part by the negative part of such estimator. Using generalized polar coordinates it is possible to obtain selective ge...

The paper introduces a construction algorithm for sparse kernel modelling using the leave-one-out test score also known as the PRESS (Predicted REsidual Sums of Squares) statistic. An efficient subset model selection procedure is developed in the orthogonal forward regression framework by incrementally maximizing the model generalization capability to construct sparse models with good generaliz...

It is surprisingly common for us to think that we are the apex of evolution. Similarly, it easy convince ourselves after nearly 3bn years, life on Earth has tried everything: every possible chemical reaction, solution and arrangement. Fortunately, both statements wrong. We now know DNA (and RNA) one solution, many, how chemistry can turn towards life. As discover new ways code genetic informati...