This article describes a series of 3 patients who presented with lower-extremity soft tissue infections. Each patient was treated with prompt debridement by an orthopedic surgeon (J.F.G.) and required at least 1 additional procedure by another surgeon.These infections vary from superficial cellulitis to rapidly advancing necrotizing fasciitis. At times, the source of these infections is clear. ...

A crucial factor in the pathogenesis of orthopedics associated infections is that bacteria do not only colonize implant surface but also surrounding tissues. This study aimed to engineer an antimicrobial release coating for stainless steel (SS) surfaces, impart them with ability prevent Staphylococci colonization. Chlorhexidine (CHX) was immobilized using two polydopamine (pDA)-based approaches...

BACKGROUND Previous studies have shown that some viral infections may be triggers for autoimmune diseases. The role of viral infections in the etiopathogenesis of pemphigus has also been investigated. OBJECTIVES To investigate the relationship between pemphigus and the hepatitis B and C virus infections. METHODS This retrospective study included 62 patients with pemphigus and 50 healthy con...

Hand infections are commonly seen by orthopedic surgeons as well as emergency room and primary care physicians. Identifying the cause of the infection and initiating prompt and appropriate medical or surgical treatment can prevent substantial morbidity. The most common bacteria implicated in hand infections remain Staphylococcus aureus and Streptococcus species. Methicillin-resistant S aureus i...

OBJECTIVES Although vitamin D is recognized as an important factor in bone health, its role in osteoarticular infections is unclear. We hypothesized that low vitamin D (25-hydroxycholecalciferol) levels are associated with a lower likelihood of treatment success in osteoarticular infections. METHODS This was a retrospective cohort study of patients with orthopedic infections who had a 25-hydr...

Joint prosthetic infections: a success story or a continuous concern? Open Access-This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited. In this issue of Acta Orthopaedica, there are 2 papers dealing with postoperative infections afte...

Orthopedic-device-related infections are notorious for causing physical and psychological trauma to patients suffering from them. Traditional methods of treating these have relied heavily on antibiotics becoming ineffectual due the rise antibiotic-resistant bacteria. Mimics antimicrobial peptides emerged as exciting alternatives their favorable antibacterial properties lack propensity generatin...