Background: Osteogenesis imperfecta (OI), is a rare hereditary disease characterized by bone fragility and low mass. The clinical presenatation various with varying severity skeletal signs inconstant extra-skeletal signs. Type 1 the most common form (60% of cases). Objectives: Our objective to describe features observed over period 15 years. Methods: This retrospective descriptive study includi...

Osteogenesis imperfecta is a disorder of the formation collagen tissue that functions as connective and caused by gene mutation causes disturbances in type 1 collagen. This study aimed to describe diagnosis osteogenesis imperfecta. A 23-year-old man came rheumatology polyclinic Dr. Mohammad Hoesin General Hospital Palembang with complaint recurrent fractures since ± 17 years ago. The patient al...