UNLABELLED Ototoxicity is still a challenge to medicine. The discovery of self-protecting endogenous mechanisms of the outer hair cells associated with their functional and ultra-structural assessment methods has opened new horizons in the understanding and controlling of these mechanisms. AIM this paper aimed at establishing whether or not underdoses of gentamicin could protect the inner ear...

The audiologic diagnosis of pseudohypacusis continues to challenge the clinical audiologist. The introduction of otoacoustic emissions (OAEs) to the test repertoire of the audiologist may prove valuable in the evaluation of pseudohypacusis. This report highlights five cases in which transient evoked otoacoustic emissions (TEOAEs) were used to cross-check the validity of subjective audiologic th...

It has been proposed that OAEs be classified not on the basis of the stimuli used to evoke them, but on the mechanisms that produce them (Shera and Guinan, 1999). One branch of this taxonomy focuses on a coherent reflection model and explicitly describes interrelationships between spontaneous emissions (SOAEs) and stimulus-frequency emissions (SFOAEs). The present study empirically examines SOA...

Stimulus-frequency otoacoustic emissions (SFOAEs) have been measured in several different ways, including (1) nonlinear compression, (2) two-tone suppression, and (3) spectral smoothing. Each of the three methods exploits a different cochlear phenomenon or signal-processing technique to extract the emission. The compression method makes use of the compressive growth of emission amplitude relati...

Phase characteristics and latency of 2f1-f2, 3f1-2f2, and 2f2-f1 acoustic distortion product otoacoustic emissions (DPOAEs) recorded in normally hearing adults have been described in a companion paper [Moulin and Kemp, "Multicomponent acoustic distortion product otoacoustic emission phase in humans. I. General characteristics," J. Acoust. Soc. Am. 100, 1617-1639 (1996)]. Phase-versus-frequency ...

Otoacoustic emissions (OAEs) evoked by broadband clicks and by single tones are widely regarded as originating via different mechanisms within the cochlea. Whereas the properties of stimulus-frequency OAEs (SFOAEs) evoked by tones are consistent with an origin via linear mechanisms involving coherent wave scattering by preexisting perturbations in the mechanics, OAEs evoked by broadband clicks ...

The purpose of this study was to determine if the menstrual cycle influences the amplitude of transient (TEOAEs) and distortion-product (DPOAEs) otoacoustic emissions. Thirteen normal-hearing, normal-cycling females were monitored weekly for 12 weeks. TEOAE and DPOAE amplitudes were analyzed to determine if amplitude changes could be detected and correlated to phases of the menstrual cycle. No ...

PURPOSE To determine cortical influence on the efferent medial olivocochlear bundle system. RESEARCH DESIGN The effects of attention on contralateral suppression (CS) of click-evoked otoacoustic emissions were measured. STUDY SAMPLE Fifteen normal-hearing listeners. RESULTS CS was greatest in the nonattending condition and decreased significantly when attending to the click or broadband n...

Measurements of middle ear (ME) acoustic power flow and related measures (e.g., reflectance, absorbance, impedance, resistance, and reactance) have several important advantages over other measures of acoustic impedance, such as the clinical “gold standard” measure, tympanometry. In addition to its wide bandwidth and ease of use, the absorbance curve, on a dB scale, has a shape that is similar t...