Natural antioxidants are less likely to cause side effects than synthetic antioxidants. As free radical scavengers, natural complex compounds can be used as antioxidant sources. The bidara plant, for example, has antibacterial, anti-inflammatory, and properties potential a scavenger (Zizipus mauritiana). goal of this study was identify their roles in complexes formed plants scavenge radicals. 2...

Colorectal Cancer (CRC) is among the most common types of cancer in world. Globally a steadily increasing proportion elderly people world result approximately 16 million new cases by year 2021. Regarding treatment; Meloxicam was shown to prevent initiation chemical-induced tumors, and considered as anticancer agent virtue its anti-proliferative effect, capacity for cell cycle arrest, pro-apopto...

Ageing and age-related neurodegenerative disorders, which are associated with free radical generation, may cause impairment of learning and memory in animals and human beings. Rutin, a bioflavonoid, is a potent free radical scavenger. Present study was designed to investigate the effect of rutin (30mg and 40mg/Kg i.p.) in 6, 9 and 12 months old mice and on sodium nitrite (75mg/kg i.p.) induced ...

Ribonucleotide Reductase (RNR) is an enzyme responsible for the reduction of ribonucleotides to their corresponding Deoxyribonucleotides (DNA), which is a building block for DNA replication and repair mechanisms. The key role of RNR in DNA synthesis and control in cell growth has made this an important target for anticancer therapy. Increased RNR activity has been associated with malignant tran...

The cytotoxicity, ROS (reactive oxygen species)-generation activity and radical-scavenging activity of curcumin and related compounds such as eugenol, eugenol orthodimer (bis-eugenol; 3,3'-dimethoxy-5,5'-di-2-propenyl-1,1'-biphenyl-2,2'-diol) and isoeugenol were investigated. Their cytotoxicity against a human submandibular gland adenocarcinoma cell line (HSG) declined in the order curcumin > i...