The purpose of this study was to evaluate the potential associations between serum asymmetric dimethylarginine (ADMA) and several anthropometric, biochemical, and lifestyle features in healthy young adults, emphasizing on the putative effects of the antioxidant intake on ADMA concentrations. Anthropometric and blood pressure measurements as well as lifestyle features and antioxidant intake were...

BACKGROUND Chronic opioid therapy for pain management has increased dramatically without adequate study of potential deleterious effects on breathing during sleep. METHODS A retrospective cohort study comparing 60 patients taking chronic opioids matched for age, sex, and body mass index with 60 patients not taking opioids was conducted to determine the effect of morphine dose equivalent on br...

BACKGROUND The natural history of surgically treated intracranial meningiomas can be quite variable. Recurrence and patient outcome cannot currently be predicted with accuracy. OBJECTIVE To explore the potential roles of tumor hypoxia-regulated biological markers, preoperative imaging, measures of proliferation, and angiogenesis in predicting patient outcome. METHODS Tissue from 263 patient...

Se evaluó el impacto emocional del acoso callejero en 395 mujeres entre los 13 y 69 años de edad a lo largo todo territorio costarricense. aplicó una escala tipo Likert Impacto Emocional Acoso Callejero (IEAC), creada para evaluar la percepción las costarricenses con respecto al callejero. Las escalas toman cuenta distintas emociones demuestran siguiente confiabilidad: α= .86 enojo/desagrado, m...

Abstract Study question What is the role of ClpX in spermatogonia differentiation and spermatogenesis? Summary answer required to maintain normal mitochondrial functions spermatocytes, deficiency resulted meiosisarrest diruption spermatogenesis mice. known already mitochondria-specific quality control protease, it maintains proteostasis via degrading misfolded or damagedproteins matrix. a AAA+ ...

OBJECTIVE To compare health care use and costs for youth with chronic health conditions before and after transfer from pediatric to adult health care services. METHODS Youth born in Ontario, Canada, between April 1, 1989, and April 1, 1993, were assigned to 11 mutually exclusive, hierarchically arranged clinical groupings, including "complex" chronic conditions (CCCs), non-complex chronic con...

BACKGROUND Heart failure (HF) is associated with inflammation characterized by the formation of the inflammasome, which triggers maturation of inflammatory cytokines. Apoptosis-associated speck-like protein with a caspase recruitment domain (ASC), a vital component of the inflammasome, is controlled through epigenetic modification, which may be a candidate pathway for worsening HF. This study e...

OBJECTIVE The objective of this study was to determine the incidence of and specific preoperative and intraoperative risk factors for postoperative delirium (POD) in electively treated vascular surgery patients. METHODS Between March 2010 and November 2013, all vascular surgery patients were included in a prospective database. Various preoperative, intraoperative, and postoperative risk facto...