Heterotopic, aberrant or ectopic pancreas is defined as the presence of pancreatic tissue in topographic anomaly, with no anatomical, neural or vascular connection to the normal pancreas. It is a rare condition found mainly in stomach, duodenum and jejunum. Ileal heterotopic pancreas is an uncommon condition and has been rarely reported in children so far. Hereby we report a case of heterotopic...

Pancreas cancer cells escape most treatment options. Heat shock protein (Hsp)90 is frequently over-expressed in pancreas carcinomas and protects a number of cell-cycle regulators such as the proto-oncogene Cdc25A. We show that inhibition of Hsp90 with geldanamycin (GD) destabilizes Cdc25A independent of Chk1/2, whereas the standard drug for pancreas carcinoma treatment, gemcitabine (GEM), cause...

Solid hamartoma of the pancreas is very rare, and only 3 cases have been reported thus far. A patient underwent pancreaticoduodenectomy due to a mass in the head of the pancreas which was suspected to be a borderline malignant tumor, but the histologic diagnosis turned out to be myoepithelial hamartoma (MEH) or adenomyoma. It was characterized by benign duct and glandular structures surrounded ...

The relationship between hemochromatosis and diabetes has been well established, as excessive iron deposition reported to result in impaired function of the endocrine exocrine pancreas. Therefore, objective present study was analyze effects accumulation on pancreata glucose homeostasis a bone morphogenetic protein 6‑knockout (Bmp6‑/‑) mouse model hemochromatosis. sera pancre...

Pancreas is an exocrine and endocrine organ. Exocrine portion secretes digestive fluid. Endocrine secreting insulin glucagon etc. developed from dorsal ventral pancreatic buds, which arise either side of distal foregut. When duodenum rotates to right, bud(VPB) posterior along with common bile duct(CBD) finally lies below behind the bud(DPB). In humans, DPB forms major part VPB inferior head unc...

Background: Sister Mary Joseph Nodule (SMJN) is a rare metastatic umbilical nodule with primary tumor genital or gastrointestinal sites. Pancreas location for metastases. Pancreatic adenocarcinoma associated SMJN usually arise from the body and tail of pancreas. We report case SMJ nodule’s as cutaneous manifestation pancreatic head cancer. Case Report: A 59-year-old man, presented epigastric, b...

OBJECTIVES Annular pancreas is a rare congenital anomaly characterized by pancreatic tissues wrapping completely or incompletely around the descending duodenum. In most patients with annular pancreas, onset occurs in early childhood. Adults with annular pancreas are prone to duodenal ulcers and pancreatitis. Intraductal papillary mucinous neoplasm (IPMN) is a type of papillary mucinous secretor...

Despite progress in the field of decellularization and recellularization, the outcome for pancreas has not been adequate. This might be due to the challenging dual nature of pancreas with both endocrine and exocrine tissues. We aimed to develop a novel and efficient cold-perfusion method for decellularization of porcine pancreas and recellularize acellular scaffolds with human fetal pancreatic ...

OBJECTIVE To describe the first case of IVF pregnancy in a pancreas-kidney recipient. DESIGN Case report. SETTING Reproductive Medicine Department, Hôpital Edouard Herriot, Lyon, France. INTERVENTION(S) In vitro fertilization in a pancreas-kidney recipient. PATIENT(S) A 39 year-old nulliparous woman, with primary infertility and a history of pancreas-kidney transplant at 29 years of age...

CONTEXT The pancreas is a soft lobulated gland situated transversely across the upper part of the posterior abdominal wall. Its parts include the head, neck, body and tail. Annular pancreas is a rare condition where the head of the pancreas surrounds the second part of the duodenum like a ring. CASE REPORT We observed a rare type of double annular pancreas where the uncinate process encircled...