نتایج جستجو برای: pancreatic ducts

تعداد نتایج: 93167  

Journal: :gastroenterology and hepatology from bed to bench 0
fernando gallucci assunta langellotto rosaria de ritis generoso uomo md

intraductal papillary mucinous neoplasms (ipmns) are rare pancreatic tumours, accounting for less of 1-2% of all neoplasms of the gland. main characteristics of ipmns are their favourable prognosis as these pre-malignant or frankly malignant lesions are usually slow-growing tumours and radical surgery is frequently possible. according with the localization of the lesions, three different entiti...

2016
Hyo‐Sup Kim Moon‐Kyu Lee

Pancreatic progenitor cell research has been in the spotlight, as these cells have the potential to replace pancreatic β-cells for the treatment of type 1 and 2 diabetic patients with the absence or reduction of pancreatic β-cells. During the past few decades, the successful treatment of diabetes through transplantation of the whole pancreas or isolated islets has nearly been achieved. However,...

Journal: :The Journal of clinical investigation 2002
Roland M Schmid

Ductal adenocarcinoma is by far the most frequent tumor of the pancreas. Although pancreatic cancer cells share substantial characteristics with pancreatic duct cells, the origin of these cancer cells is still a matter of debate. Progressive changes in the ductal epithelium range from non-papillary to papillary hyperplasia, with little or no development of atypical or dysplastic epithelial lesi...

Journal: :Cancer research 2007
Ryan M Thomas Kenya Toney Cecilia Fenoglio-Preiser Monica P Revelo-Penafiel Sunil R Hingorani David A Tuveson Susan E Waltz Andrew M Lowy

Pancreatic cancer is an aggressive disease characterized by rapid growth and early metastasis. The recepteur d'origine nantais (RON) receptor tyrosine kinase is overexpressed and/or constitutively active in several epithelial cancers, but its role in pancreatic cancer is unknown. In this study, we have characterized RON expression in both murine and human pancreatic cancer. Immunoblotting indic...

2007
Ryan M. Thomas Kenya Toney Cecilia Fenoglio-Preiser Monica P. Revelo-Penafiel Sunil R. Hingorani David A. Tuveson Susan E. Waltz Andrew M. Lowy

Pancreatic cancer is an aggressive disease characterized by rapid growth and early metastasis. The recepteur d’origine nantais (RON) receptor tyrosine kinase is overexpressed and/or constitutively active in several epithelial cancers, but its role in pancreatic cancer is unknown. In this study, we have characterized RON expression in both murine and human pancreatic cancer. Immunoblotting indic...

Journal: :Oncology reports 2008
Xiaohua Jiang Weiwei Zhang Hany Kayed Pan Zheng Nathalia A Giese Helmut Friess Jörg Kleeff

ONECUT1 (HNF-6) is the prototype of a new class of homeodomain transcription factors, that controls the development of pancreatic ducts during mouse development. In the present study, the role of ONECUT1 and its targeted genes TCF2, PKHD1 and CYS1 was analyzed in human pancreatic ductal adenocarcinoma (PDAC). mRNA levels of ONECUT1, TCF2, PKHD1 and CYS1 were measured in pancreatic tissues and p...

2018
Yuki Ishikawa-Kakiya Masatsugu Shiba Hirotsugu Maruyama Kunihiro Kato Shusei Fukunaga Satoshi Sugimori Koji Otani Shuhei Hosomi Fumio Tanaka Yasuaki Nagami Koichi Taira Hirokazu Yamagami Tetsuya Tanigawa Toshio Watanabe Yasuhiro Fujiwara

BACKGROUND & AIMS Advanced techniques have been developed to overcome difficult cannulation cases in endoscopic retrograde cholangiopancreatography (ERCP). Pancreatic duct guidewire placement method (PGW) is performed in difficult cannulation cases; it is possible that it places patients at risk of post-ERCP pancreatitis (PEP). The mechanism of PEP is still unclear, but pancreatic duct pressure...

2017
Teresa Berrocal Javier Larrauri

This analysis is based on imaging findings from our own database of pediatric pancreatic pathology. We performed ultrasound in all cases and CT and/or MRI when ultrasound was inconclusive. MR cholangiopancreatography (MRCP) was used to study the pancreatic ducts. The pancreas is a nonencapsulated, multilobar gland that extends from the second portion of the duodenum to the splenic hilum.1 It fo...

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