spike sorting is a class of techniques used in the analysis of electrophysiological data. studying the dynamics of neural activity via electrical recording relies on the ability to detect and sort neural spikes recorded from a number of neurons by the same electrode. this article reviews methods for detecting and classifying action potentials, a problem commonly referred to as spike sorting.

Given that macrophages can proliferate and that certain microbes survive inside phagocytic cells, the question arises as to the post-mitotic distribution of microbial cargo. Using macrophage-like cells we evaluated the post-mitotic distribution of intracellular Cryptococcus yeasts and polystyrene beads by comparing experimental data to a stochastic model. For beads, the post-mitotic distributio...

This paper presents a new multiobjective evolutionary algorithm applied to a radial basis function (RBF) network design based on mult iobjective particle swarm optimization augmented with local search features. The algorithm is named the memetic multiobjective particle swarm optimization RBF network (MPSON) because it integrates the accuracy and structure of an RBF network. The proposed algorit...

Arenaviruses cause severe diseases in humans but establish asymptomatic, lifelong infections in rodent reservoirs. Persistently-infected rodents harbor high levels of defective interfering (DI) particles, which are thought to be important for establishing persistence and mitigating virus-induced cytopathic effect. Little is known about what drives the production of DI particles. We show that ne...

The paper presents a comparison of the concentration methods conventional jig, air and sensor-based sorting to treat construction demolition waste. All tests were made with concrete, brick, gypsum particles aim separate these materials into different size ranges, depending on method. equipment tested, present good results concentrate waste particles, concentrations mass recoveries. show particu...

Cytoplasmic actins have been found interacting with viral proteins and identified in virus particles. We analyzed by confocal microscopy the cytoplasmic β- and γ-actin patterns during the course of Sendai virus infections in polarized cells. We observed a spectacular remodeling of the β-cytoplasmic actin which correlated with productive viral multiplication. Conversely, suppression of M during ...

Endocytosis in eukaryotic cells is characterized by the continuous and regulated formation of prolific numbers of membrane vesicles at the plasma membrane. These vesicles come in several different varieties, ranging from the actin-dependent formation of phagosomes involved in particle uptake, to smaller clathrin-coated vesicles responsible for the internalization of extracellular fluid and rece...

Translational control has recently been recognized as an important facet of adaptive responses to various stress conditions. We describe the adaptation response of the yeast Saccharomyces cerevisiae to the loss of one of two mechanisms to target proteins to the secretory pathway. Using inducible mutants that block the signal recognition particle (SRP) pathway, we find that cells demonstrate a p...

Proteins interact with each other in a highly specific manner, and protein interactions play a key role in many cellular processes. Since protein interactions determine the outcome of most cellular processes, so identifying and characterizing Protein– Protein interactions and their networks are essential for understanding the mechanisms of biological processes on a molecular level. This paper e...