OBJECTIVE Several modifications for increasing the efficacy and safety of the minimally invasive surgery (Nuss procedure) for repair of pectus excavatum in pediatric patients were presented. In this study, we apply a modified bilateral thoracoscopic approach to adapt the Nuss procedure to adult patients. METHODS We prospectively included all adult patients with pectus excavatum corrected by m...

Purpose: The Nuss procedure for pectus excavatum has rapidly gained acceptance among pediatric surgeons. We present the results and lessons learned from our initial 50 patients undergoing the minimally invasive pectus repair. Patients and methods: After obtaining Internal Review Board approval, we retrospectively reviewed patients undergoing the Nuss procedure from April 1998 to September 2002....

BACKGROUND/AIM Pectus excavatum and pectus carinatum are the most commonly seen anterior chest wall deformities. Recent studies reveal that minimal invasive repair of pectus deformities improves the quality of life. Our aim is to assess the psychosocial functioning and sociodemographic characteristics of pediatric patients with pectus deformities and evaluate the differences between patients op...

Pectus excavatum and pectus carinatum represent the most frequent chest wall deformations. However, the pathogenesis is still poorly understood and research results remain inconsistent. To focus on the recent state of knowledge, we summarize and critically discuss the pathological concepts based on the history of these entities, beginning with the first description in the sixteenth century. Bas...

A 53-year-old man was admitted to our center with dyspnea and peripheral edema compatible with cardiac failure. His history was notable for Noonan syndrome, but he had not been seen a physician for 15 years. On examination, pectus excavatum, pectus carinatum, and low implantation of the ears were present (Figure 1). Blood pressure was 145/ 70 mm Hg, and pulse was irregular at 90 to 100 beats pe...

A polygamous Nigerian family with inherited skeletal cardiovascular anomalies (Holt-Oram syndrome) is described. Common to the affected individuals in this family were pectus excavatum and abnormalities of the thumbs. Atrial septal defect was proven by angiocardiography in one and clinically diagnosed in another member of the family. The mode of inheritance of the abnormalities in this family a...

A 28 month old girl with dysmorphic features was found to have an interstitial deletion of the short arm of chromosome 7p15.3-7p21.2. The patient had ptosis, dacryostenosis, pectus excavatum, short hands, and her development was normal or mildly delayed. Craniosynostosis and growth retardation, which were present in two other patients with similar deletions, were not present. Because of the mil...

Fetal warfarin syndrome is a consequence of maternal intake of warfarin during pregnancy and comprises a wide range of manifestations, including some typical facial dysmorphologic features. The authors report a case of prenatal ultrasonographic diagnosis of warfarin embryopathy in an obese woman on unsupervised warfarin prophylaxis at the 16th week of gestation. The fetus presented with facial ...