background peptic ulcer disease is a multifactorial health problem affecting almost all populations worldwide. large scale population-based studies are crucial to understanding its scope and specifications in various nations. we aimed to explore environmental risk factors of peptic ulcer disease in the first population based study in ardabil, northwest iran. methods this study was a part of a l...

objective: it has been noted that the presence of helicobacter pylori (h. pylori) in the oral cavity may affect the outcome of eradication therapy. this condition is associated with the recurrence of gastric infection. the optimum secretion of saliva promotes oral health consequently influencing h. pylori eradication. the purpose of this study was to investigate the relation between salivary se...

background: cd1d presents glycolipid antigens to invariant natural killer t (inkt) cells. the role of cd1d in the development of peptic ulcer and gastric cancer has not been revealed, yet. objective: to clarify the expression of alternatively spliced variants of cd1d in peptic ulcer and gastric cancer. methods: patients with dyspepsia were selected and divided into three groups of non-ulcer dys...

purpose: to compare the prevalence of glaucoma among peptic ulcer patients with or without helicobacter pylori infection. methods: among 352 patients with an indication of gasterointestinal endoscopy for peptic problems, 120 patients in 18-88 years of age were included for evaluation of glaucoma. according to the results of histopathologic and urease test, they were divided into two groups: hel...

Background—Virulence factors of Helicobacter pylori are associated with peptic ulcer disease and may be also associated with the eYcacy of treatment. Aims—To determine the relation between the vacA and the cagA status of H pylori, clinical disease, and treatment outcome. Patients—121 patients with H pylori infection and peptic ulcer disease or functional dyspepsia were treated by quadruple anti...

Interleukin 12 (IL-12) is a proinflammatory cytokine composed by two chains, p40 and p35, that plays a key role in the promotion of a Th1 immune response in the gastrointestinal mucosa. An enhanced expression of IL-12 mRNA in gastric mucosa has been reported in individuals infected by Helicobacter pylori. The aim of our study was to assess whether a functional polymorphism located at position 1...

Ulcer is a common gastrointestinal disorder which is seen among many people. It is basically an inflamed break in the skin or the mucus membrane lining the alimentary tract. Ulceration occurs when there is a disturbance of the normal equilibrium caused by either enhanced aggression or diminished mucosal resistance. It may be due to the regular usage of drugs, irregular food habits, stress, and ...