Neonatal appendicitis is a rare clinical entity associated with remarkable morbidity and mortality. Appendicular perforation is common and the diagnosis is usually made intra-operatively. The causative etiology of neonatal perforated appendicitis (NPA) is a subject of debate and has not been elucidated. Although many etiologic theories exist, increasing evidence suggests a subset of NPA cases m...

A 1 year review of 529 cases of acute appendicitis, treated at the University Hospital in 1990, was performed. Perforation rate was 23.7% and delay in diagnosis was found to be significant. Patients above 50 years of age were particularly at risk. Diagnostic error was 19.3% and it was a problem not only in young women but also in children. Temperature and rectal examinations were not found to b...

BACKGROUND Perforated appendicitis is one of the most common causes of acute abdomen requiring emergent surgery for immediate appendectomy and peritoneal cavity irrigation; however, the efficacy of irrigation with antibiotic solutions is controversial. OBJECTIVES The aim of this study was to assess the efficacy of imipenem solution irrigation on post-operative surgical site infections (SSIs),...

A young boy presented with history of abdominal trauma. History and initial clinical findings suggested a soft tissue injury. Due to increasing abdominal pain and fever, we proceeded with an exploratory laparotomy with a diagnosis of intra-abdominal injury, at which we found a perforated appendix. Appendicitis following blunt abdominal trauma needs high index of suspicion.

Acute appendicitis is the most common cause of acute surgical abdomen during pregnancy. Our study was conducted to review our experience and diagnostic accuracy with MRI during pregnancy and clinical outcomes over a two year period. All pregnant women who underwent an MRI examination of the abdomen between January 2008 and January 2010 at Spectrum Health hospitals were included in the study. We...

OBJECTIVE To compare the safety and efficacy of antibiotic treatment versus appendicectomy for the primary treatment of uncomplicated acute appendicitis. DESIGN Meta-analysis of randomised controlled trials. POPULATION Randomised controlled trials of adult patients presenting with uncomplicated acute appendicitis, diagnosed by haematological and radiological investigations. INTERVENTIONS ...

KEY CLINICAL MESSAGE We report a case of a successful embolization of a mycotic aneurysm of the left uterine artery in the puerperium after a neglected perforated appendicitis. A mycotic aneurysm, meaning an infection of the vessel wall which leads to an aneurysmatic dilatation of the vessel, is potentially life threatening if rupture occurs.

OBJECTIVE To compare the effectiveness and adverse event rates of early vs interval appendectomy in children with perforated appendicitis. DESIGN Nonblinded randomized trial. SETTING A tertiary-referral urban children's hospital. PATIENTS A total of 131 patients younger than 18 years with a preoperative diagnosis of perforated appendicitis. INTERVENTIONS Early appendectomy (within 24 ho...

Infection and inflammation of organs adjacent to the gastrointestinal tract may cause a pathological connection. In this report, complicated appendicitis caused protrusion of the right ovary and tube into the sigmoid colon of a 40-year-old woman. The mass, appearing as a polypoid lesion during colonoscopy, caused abdominal pain and bleeding and proved to be right adnexa pathologically.

Primary appendiceal neoplasms are rare and usually found incidentally after appendicectomy for suspected appendicitis. We report a case of a perforated cystadenocarcinoma of the appendix occurring synchronously with caecal adenocarcinoma in an 81-year-old woman without abdominal symptoms or signs, who presented with iron deficiency anaemia.