In pulmonary arterial hypertension (PAH) structural and functional abnormalities of the small lung vessels interact and lead to a progressive increase in pulmonary vascular resistance and right heart failure. A current pathobiological concept characterizes PAH as a 'quasi-malignant' disease focusing on cancer-like alterations in endothelial cells (EC) and the importance of their acquired apopto...

BACKGROUND Although an association between insulin resistance (IR) and body adiposity has been reported in obese children, this relationship has not been studied as thoroughly as in adults. AIM We evaluated the association between oral glucose tolerance testing (OGTT) and percent body fat (PBF) in a sample of 1512 obese children followed at a Pediatric Obesity Clinic. SUBJECTS AND METHODS S...

BACKGROUND The aim of the study was to assess the association between chronic kidney disease (CKD) and obesity in predicting CKD among Chinese adults, distinguishing between 5 different adiposity indices: visceral fat index (VFI), percentage body fat (PBF), body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR). METHODS A total of 29,516 participants aged 35 years or...

Elicitor-induced activation of the potato pathogenesis-related gene PR-10a requires a 30-bp promoter sequence termed the ERE (elicitor response element) that is bound by the nuclear factor PBF-2 (PR-10a binding factor 2). In this study, PBF-2 has been purified to near homogeneity from elicited tubers through a combination of anion-exchange and DNA affinity chromatography. Evidence demonstrates ...

OBJECTIVES The purpose of this study was to investigate the involvement of TRPA1 in the cinnamaldehyde-induced pulpal blood flow (PBF) change in the feline dental pulp. MATERIALS AND METHODS Mandibles of eight cats were immobilized and PBF was monitored with a laser Doppler flowmetry at the mandibular canine tooth. To evaluate the effect of cinnamaldehyde on PBF, cinnamaldehyde was injected i...

Abstract This paper explores the possibilities to use laser-based additive processes make, surface treat and repair/remanufacture tools, dies molds for cold working, hot injection molding. The failures encountered in these applications are described. materials used conventionally laser accounted for. properties of made by Laser-based Powder Bed Fusion (L-PBF) as good some cases better than thos...

China’s rapid industrialization despite the lack of a well developed financial system seems to defy the conventional thinking on the role of finance in development. This paper tries to explain the puzzle from the clustering point of view. Based on firm-level data from two recent censuses, we find that within industrial clusters: finer division of labor lowers the capital barriers to entry; clos...

in the context of international trade factoring as one of the important ways of financing, is a dominant method of asset based financing for small and medium enterprises. financing through factoring be done in the form of a contract between the creditor and factor, and determining the legal nature of this contract is important to identify and determine its effects. with this regard, this paper ...

A continuum-scale modeling approach is developed and employed with three-dimensional finite element analysis (FEA), for simulating the temperature response of a Ti-6Al-4V, two-layered parallelepiped with dimensions of 10×5×0.06 mm during Laser Powder Bed Fusion (L-PBF), a metals additive manufacturing (AM) method. The model has been validated using experimental melt pool measurements from the l...