This study was undertaken for the identification of matrix metalloproteinases (MMPs) in extracts obtained from native, acellular and crosslinked bovine pericardium (in vitro), as well as in the plasma after implantation of these biomaterials in rabbits (in vivo). Native pericardium (NP) expressed a 72 kDa (MMP-2) band; whereas, in acellular pericardium (AP) two bands (10 kDa and 92 kDa) of MMPs...

Four patients are presented who developed acute mitral regurgitation 5 days, 2, 3, and 18 months, respectively, before cardiac catheterization. The hemodynamic findings in the three early cases resemble those found in the presence of a constricting pericardium: left and right ventricular, as well as left and right atrial pressures, equilibrated during diastole. As expected, giant left atrial v ...

Posterior (17) and anterior (3) mitral cusp pericardioplasties were performed in 20 patients between 6 December 1961 and 10 July 1963. A long-term follow-up study was done in nine patients. In six of these, mitral valvectomy with Starr-Edwards ball valve replacement was required after intervals varying between two years and three months and seven years and three months. In only one of the six c...

Cardiovascular diseases hold the highest mortality rate among other illnesses which reveals the significance of current limitations in common therapies. Three-dimensional (3D) scaffolds have been utilized as potential therapies for treating heart failure following myocardial infarction (MI). In particular, native tissues have numerous properties that make them potentially useful scaffolding mat...

Thank you for your Letter to the Editor [1] regarding our report ‘Tricuspid valve repair in a case with congenital absence of left thoracic pericardium’. We appreciate your comments and agree that congenital elements in partial and complete absence of pericardum must be considered. Associated anomalies including mitral stenosis, atrial septal defect, patent ductus arteriosus and tetralogy of Fa...

knowledge, to show gross pericardial calcification in the roentgenograms. Pericardial calcification is probably related to the duration of pericarditis,' and it is possible that, in our patient, the disease may have been undetected for some years. Microscopic calcification was previously noted in pericardial specimens obtained from a patient with "rheumatoid pericarditis."s The possibility of t...

PURPOSE Biomaterials have been widely used in the field of regenerative medicine. Bovine pericardium tissue has been successfully used as a bioprosthetic material in manufacturing heart valves, but studies concerning the tissue are ongoing in order to improve its storage, preservation and transportation. This article provides an overview of the characteristics of bovine pericardium tissue chemi...

Controversy exists whether positive end-expiratory pressure (PEEP) ventilation lowers cardiac output by reducing left ventricular preload, or by a combination of mechanisms. Sixteen open-chest dogs were instrumented for measurement of left and right ventricular pressure, aortic flow, and left ventricular dimensions. With the pericardium intact, PEEP caused the interventricular septum to bulge t...

We have tested the mechanical properties of isolated canine pericardium at 37°C in Hanks' solution, and compared those results with similar tests on tissue at room temperature, both in Hanks' solution and merely kept moist with saline. Pericardium, which is nearly isotropic due to the layers of collagen aligned in different directions, is a composite material made up of collagen and elastin fib...

OBJECTIVE The aim of this study was to describe the use of equine pericardium sheet (Lyomesh (®) ) as dural substitute for sellar reconstruction after endoscopic endonasal transsphenoidal surgery for the removal of pituitary adenomas. METHODS We reviewed data of patients that underwent surgery by means of an endoscopic endonasal transsphenoidal approach for the removal of pituitary adenomas o...