A single case is described of congenital leukaemia with 11q23/MLL rearrangement in a preterm female newborn. Because of arachnophobia, the mother had heavily abused aerosolised permethrin, a widely used household insecticide. Permethrin is considered comparatively safe, but, in view of the mother's history, its potential to induce cleavage of the MLL gene in cell culture was tested. Incubation ...

Accounting for approximately 11% of all malaria cases, the Democratic Republic of the Congo (DRC) is central to malaria elimination efforts. To support vector control interventions in DRC, we characterized the dynamics and impact of insecticide resistance in major malaria vectors in 2015. High Plasmodium infection rates were recorded in Anopheles gambiae and Anopheles funestus, with Plasmodium ...

Insecticides are a key component of vector-based malaria control programmes in Cameroon. As part of ongoing resistance surveillance efforts, Anopheles gambiae s.l. female mosquitoes were exposed to organochlorine (DDT), a carbamate (bendiocarb), an organophosphate (malathion), and three pyrethroids (deltamethrin, lambda-cyhalothrin and permethrin) in WHO bioassay test kits. Results indicated a ...

In Japan, maximum residue levels (MRL) have been set for eight pesticides (a-BHC, b-BHC, g-BHC, d-BHC (BHCs), p,p′-DDE, o,p′-DDT, p,p′-DDD, p,p′-DDT (DDTs)) in 14 crude drugs (below 0.2 ppm as total of BHCs, below 0.2 ppm as total of DDTs). There are fears that pesticides present in crude drugs for which MRL are set will be changed from BHCs and DDTs to other pesticides with MRL setting as the ...

Background: One approach for prevention of cutaneous leishmaniasis is creation of a barrier between the insect vector (phlebotomus) and the host.  Many, but not all, researchers claim that permethrin-impregnated uniforms are effective for prevention of cutaneous leishmaniasis.  We determined the efficacy of permethrin-impregnated uniforms for prevention of cutaneous leishmaniasis among Iranian ...

Background: Aquatic ecosystems are frequently subjected to contamination by toxic heavy metals and pesticides, yet very little is known about the influence of pesticides on bioaccumulation of heavy metals in aquatic organisms. Mercury is a toxic metal with no known biological benefit to organisms. Bioavailability of mercury in aquatic environments depends on biological and non-biological parame...

Four acaricides (amitraz, cyfluthrin, permethrin, and pyrethrins) were studied for their efficacy in the rapid killing of Amblyomma americanum, A. cajennense, and A. maculatum (Acari: Ixodidae) and eight acaricides (amitraz, carbaryl, chlorpyrifos, cyfluthrin, fipronil, permethrin, pyrethrins, and selamectin) for their efficacy in the rapid killing of Rhipicephalus sanguineus (Acari: Ixodidae)....

BACKGROUND Permethrin, a pyrethroid insecticide, is not yet available in Iran and may be a useful substitute for the control of scabies in Iran. AIM To compare the efficacy of topical lindane with topical permethrin in the treatment of scabies in a population in Iran. METHODS In a double-blind, randomized study, all consecutive patients with scabies were randomized into two groups. One grou...

Background. Malaria remains an important public health issue in Benin, with Anopheles gambiae s.l. and Anopheles funestus s.s being the predominant vectors. This study was designed to generate information on An. funestus distribution, molecular speciation, Plasmodium infection rate and insecticide susceptibility status across Benin. Methods. Mosquito samples were collected from December 2014 to...